| Tag | Content |
|---|---|
| Uniprot ID | K7C8W0; A0A2J8KTB0; H2RD60; |
| Entrez ID | 452661 |
| Genbank protein ID | JAA28938.1; JAA38281.1; |
| Genbank nucleotide ID | XM_001136859.3 |
| Ensembl protein ID | ENSPTRP00000058373 |
| Ensembl nucleotide ID | ENSPTRG00000006032 |
| Gene name | Collagen type IV alpha 2 chain |
| Gene symbol | COL4A2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGRDQRAVAG PALRRWLLGT VTVGFLAQSV LAGVKKFDVP CGGRDCSGGC QCYPEKGGRG 60 QPGPVGPQGY NGPPGLQGFP GLQGRKGDKG ERGAPGITGP KGDVGARGVS GFPGADGIPG 120 HPGQGGPRGR PGYDGCNGTQ GDSGPQGPPG SEGFTGPPGP QGPKGQKGEP YALPKEERDR 180 YRGEPGEPGL VGFQGPPGRP GHVGQMGPVG APGRPGPPGP PGPKGQQGNR GLGFYGVKGE 240 KGDVGQPGPN GIPSDLLHPI IAPTGVTFHP DQYKGEKGSE GEPGIRGISL KGEEGIMGFP 300 GLRGYPGLSG EKGSPGQKGS RGLDGYQGPD GPRGPKGEAG DPGPPGLPAY SPHPSLAKGA 360 RGDPGFPGAQ GEPGSQGEPG DPGLPGAPGL SIGDGDQRRG LPGEMGPKGF IGDPGIPALY 420 GGPPGPDGKR GPPGPPGLPG PPGPDGFLFG LKGAKGRAGF PGLPGSPGAR GPKGWKGDAG 480 ECRCTEGDEA IKGLPGLPGP KGFAGINGEP GRKGDKGDPG QHGLPGFPGL KGVPGNVGAP 540 GPKGAKGDSR TITTKGERGQ PGVPGVPGMK GDDGSPGRDG LDGFPGLPGP PGDGIKGPPG 600 DPGYPGIPGT KGTPGEMGPP GLGLPGLKGQ RGFPGDAGLP GPPGFLGPPG PAGTPGQIDC 660 DTDVKRAIGG DRQEAIQPGC VGGPKGLPGL PGPPGPTGAK GLRGIPGFSG ADGGPGPKGL 720 PGDAGREGFP GPPGFIGPRG SKGAVGLPGP DGSPGPIGLP GPDGPPGERG LPGEVLGAQP 780 GPRGDAGVPG QPGLKGLPGD RGPPGFRGSQ GMPGMPGLKG QPGLPGPSGQ PGLYGPPGLH 840 GFPGAPGQEG PLGLPGIPGR EGLPGDRGDP GDTGAPGPVG MKGLSGDRGD AGFTGERGHP 900 GSPGFKGIDG MPGTPGLKGD RGSPGMDGFQ GMPGLKGRPG FPGSKGEAGF FGIPGLKGLA 960 GEPGFKGSRG DPGPPGPPPV ILPGMKDIKG EKGDEGPMGL KGYLGAKGIQ GMPGIPGLSG 1020 IPGLPGRPGH IKGVKGDIGA PGIPGLPGFP GVAGPPGITG FPGFIGSRGD KGAPGRAGLY 1080 GEIGATGDFG DIGDTINLPG RPGLKGERGT TGIPGLKGFF GEKGTEGDIG FPGITGVTGV 1140 QGPPGLKGQT GFPGLTGPPG SQGEPGRIGL PGGKGDDGWP GAPGLPGFPG LRGIRGLHGL 1200 PGTKGFPGSP GSDIHGDPGF PGPPGERGDP GEANTLPGPV GVPGQKGDQG APGERGPPGS 1260 PGLQGFPGIT PPSNISGAPG DKGAPGIFGL KGYRGPPGPP GSAALPGSKG DTGNPGAPGT 1320 PGTKGWAGDS GPQGRPGVFG LPGEKGPRGE QGFMGNTGPT GAVGDRGPKG PKGDPGFPGA 1380 PGTVGAPGIA GIPQKIAVQP GTVGPQGRRG PPGAPGEMGP QGPPGEPGFR GAPGKAGPQG 1440 RGGVSAVPGF RGDEGPIGHQ GPIGQEGAPG RPGSPGLPGM PGRSVSIGYL LVKHSQTDQE 1500 PMCPVGMNKL WSGYSLLYFE GQEKAHNQDL GLAGSCLARF STMPFLYCNP GDVCYYASRN 1560 DKSYWLSTTA PLPMMPVAED EIKPYISRCS VCEAPAVAIA VHSQDVSIPH CPAGWRSLWI 1620 GYSFLMHTAA GDEGGGQSLV SPGSCLEDFR ATPFIECNGG RGTCHYYANK YSFWLTTIPE 1680 QSFQGSPSAD TLKAGLIRTH ISRCQVCMKN L 1711 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A2 | A0A452G6J0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL4A2 | 1284 | P08572 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Col4a2 | 12827 | P08122 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | 452661 | K7C8W0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | F1RLL9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Col4a2 | F1M6Q3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005587 | collagen type IV trimer |
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0035987 | endodermal cell differentiation |
| GO:0030198 | extracellular matrix organization |
| GO:0016525 | negative regulation of angiogenesis |
| GO:0006351 | transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |