| Tag | Content |
|---|---|
| Uniprot ID | F1M6Q3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000054270 |
| Ensembl nucleotide ID | ENSRNOG00000023972 |
| Gene name | Collagen type IV alpha 2 chain |
| Gene symbol | Col4a2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | GQPGEVGPQG YNGPPGLQGF PGLQGRKGDK GERGAPGPTG PKGDVGARGV SGFPGADGIP 60 GHPGQGGPRG RPGYDGCNGT RGDAGPQGPS GTGGFPGLPG PQGPKGQKGE PYALSKEDRD 120 KYRGLPGEPA RSGYQGPPGR PGPIGQMGPM GAPGRPGPPG PPGPKGQPGN RGLGFYGEKG 180 EKGDVGQPGP NGIPSDITLI GPTPSTYHPD MYKGEKGSQG EPGIPGITLK GEEGIMGFPG 240 TRGFPGLDGE KGVSGQKGSR GLDGFQGPSG PRGPKGERGE LGPPGPPAYS PHPSLAKGAR 300 GDPGFQGAHG EPGSRGEPGD PGPVGPPGLS IGDEDSKRGL PGEMGPKGFS GEPGPSAYYP 360 GPPGADGKPG PQGLPGPAGP PGPDGFLFGL KGSEGRVGYP GPSGFPGGRG QKGWKGEAGD 420 CQCGQVIPGL PGLPGPKGFP GVNGEFGKKG DQGDPGLHGI PGFPGFKGAP GIAGAPGPKG 480 VKGDSRTITT KGERGQPGIP GVHGMKGDDG VPGRDGLDGF PGLPGPPGDG IKGPPGDAGL 540 PGTPGTKGFP GEVGPPGQGL PGPKGERGFP GDAGLPGPPG FPGPPGLPGT PGQADCDTGV 600 KRPIGGGQQV VIQPGCVEGP AGSPGQPGPP GPTGAKGIRG IPGFPGASGE QGLKGFPGDP 660 GREGFPGPPG FMGPRGSKGA PGLPGPDGPP GPIGLPGPAG PPGDRGIPGE VLGAQPGARG 720 DAGLPGQPGL KGFPGEIGAP GFRGDQGMPG MPGLKGQPGF PGPSGQPGLS GPPGQHGFPG 780 APGREGPLGL PGSPGLGGLP GDRGEPGEPG PGPVGMKGVS GDRGDAGVSG ERGHPGSPGF 840 GMAGMPGIPG QKGDRGSPGM DGFQGMLGLK GRPGFPGIKG EAGFFGVPGL KGLPGEPGVK 900 GNRGDRGPPG PPPLILPGMK DIKGEKGDEG PMGLKGYLGL KGIQGMPGVP GLSGIPGLPG 960 RPGFIKGAKG DIGVPGTPGL PGFPGVSGPP GITGFPGFTG SRGEKGTPGV AGVFGETGPT 1020 GDFGDIGDTV DLPGSPGLKG ERGVTGIPGL KGLFGEKGAE GDVGFPGITG MAGAQGSPGL 1080 KGQTGFPGLT GLQGPQGEPG RIGIPGDKGD FGWPGVPGRP GIPGIRGISG LHGLPGTKGF 1140 PGSPGVDAHG DPGFPGPTGD RGDRGEANTL PGPVGAPGQK GEQGIPGERG PVGSPGLQGF 1200 PGISPPSNIS GLPGDVGAPG IFGLQGYQGP PGPPGPNALP GIKGDEGSSG AAGFPGEKGW 1260 VGDPGPQGQP GVHGLPGEKG PKGEQGFMGN TGPSGAVGDR GPKGPKGDQG FPGAPGSMGS 1320 PGIPGIPQKI AVQPGTMGPQ GRRGLPGALG EMGPQGPPGD PGFRGAPGKA GPQGRGGVSA 1380 VPGFRGDQGP MGHQGPIGQE GEPGRPGSPG LPGMPGRSVS IGYLLVKHSQ TDQEPMCPVG 1440 MNKLWSGYSL LYFEGQEKAH NQDLGLAGSC LARFSTMPFL YCNPGDVCYY ASRNDKSYWL 1500 STTAPLPMMP VAEEEIKPYI SRCSVCEAPA VAIAVHSQDV SIPHCPAGWR SLWIGYSFLM 1560 HTAAGDEGGG QSLVSPGSCL EDFRATPFIE CNGGRGTCHY FANKYSFWLT TIPEQNFQST 1620 PSADTLKAGL IRTHISRCQV CMKNL 1645 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A2 | A0A452G6J0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL4A2 | 1284 | P08572 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Col4a2 | 12827 | P08122 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | 452661 | K7C8W0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | F1RLL9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Col4a2 | F1M6Q3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005604 | basement membrane |
| GO:0005587 | collagen type IV trimer |
| GO:0031012 | extracellular matrix |
| GO:0005576 | extracellular region |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0007568 | aging |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0035987 | endodermal cell differentiation |
| GO:0030198 | extracellular matrix organization |
| GO:0016525 | negative regulation of angiogenesis |
| GO:0014823 | response to activity |
| GO:0006351 | transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |