| Tag | Content |
|---|---|
| Uniprot ID | F1RLL9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000010191 |
| Ensembl nucleotide ID | ENSSSCG00000009545 |
| Gene name | Collagen type IV alpha 2 chain |
| Gene symbol | COL4A2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDRDPRAASG PALRRWLLLG TVMVGLLAQS VLAGVKKLDV PCGGRDCSGG CQCYPEKGGR 60 GQPGPVGPQG YTGPPGLQGF PGLQGRKGDK GERGAPGITG PKGDVGARGV SGFPGADGIP 120 GHPGQGGPRG RPGSDGCNGT VGDTGYAGPV GPDGFLGPPG PQGPKGQKGE PYALSREDRD 180 KYRGEPGEPG LVGFQGPPGR PGPVGQMGPV GAPGRPGPPG PPGPKGQPGN RGLGFYGEKG 240 EKGDVGQPGP NGIPSDNHHP IIGPTRETIY LDQYKGEKGS EGEPGRKGIS LKGEEGIMGF 300 SGSRGVPGFD GEKGSPGQKG SRGLDGYEGP DGYPGPKGER GDPGPPGAPA YSPHPSLAKG 360 ARGEPGFPGA LGEPGARGEP GDPGPPGLPG TSVRDEDEKR GLPGEMGPKG YAGEPGAPAL 420 YPGPPGADGK PGLRGPPGPP GPPGPDDFLF GLKGAKGSMG YPGPSGFPGA RGQKGWKGDA 480 GDCKCAEDDQ FVGGLPGPPG PKGFPGINGE PGRKGSQGDP GQHGIPGFPG FKGAPGDAGP 540 PGPKGMKGDS RTITTKGERG QPGVPGVPGL RGDDGAPGRD GLDGFPGLPG PPGDGIKGPP 600 GDAGHPGVPG TKGLAGDRGP PGLGLPGPKG ERGFPGDDGL PGPPGFPGPP GPPGPPGQID 660 CDSGVKRPIG ADGQEVIQPG CVGGPKGSPG QPGPPGPPGA KGLRGIPGPS GADGAPGLKG 720 FPGDPGREGF PGPPGFVGPR GSKGAVGPPG LDGLPGPSGL PGPVGPPGDK GLPGEVLGAQ 780 PGSRGDPGLP GHPGLKGPPG ERGAPGFRGS EGMPGMPGLK GQPGFPGPSG QPGLPGPPGQ 840 HGFPGAPGRE GPLGPPGAPG FGGLPGDRGD PGDTGVPGPV GMKGLSGDRG DPGLLGERGH 900 PGSPGFKGVA GMPGAPGPKG TRGSPGMHGF QGMLGLKGSP GLPGSKGEAG FFGVPGLKGL 960 PGEPGVKGSR GDPGLPGPPP TILPGMKDIK GEKGDEGPMG LKGYLGLKGI PGMPGIPGLS 1020 GVPGLPGKPG HVKGAKGDTG APGVPGSPGF PGLPGPPGII GFPGFTGSRG DKGSPGRAGL 1080 YGEIGATGDF GDIGDTIDLP GSPGLKGERG TAGVPGLKGF FGEKGTVGDV GFPGITGLAG 1140 VQGPPGLKGQ TGFPGLTGLQ GPQGDPGRAG VPGAKGELGW PGNVGLPGLP GIRGISGLHG 1200 LPGTKGFPGS PGADVHGDPG FPGPAGDRGD PGEANTLPGP AGAPGQKGER GAPGERGPVG 1260 NPGLQGFPGI TPPSNVSGLP GDTGAPGIFG PEGYRGPPGP PGPAALPGSK GDEGLPGIPG 1320 NPGGKGWVGD PGPQGRPGVF GLPGEKGPRG EQGFMGNTGA TGSVGDRGPK GPKGDRGLPG 1380 PPGAVGAPGI VGIPQRIAVQ RGPVGPQGRR GPPGAQGEMG PQGPPGEPGF RGAPGKAGPQ 1440 GRGGVSAVPG FRGDQGPVGQ QGPVGQEGEP GRPGSPGLPG MPGRSVSIGY LLVKHSQTDQ 1500 EPMCPVGMNK LWSGYSLLYF EGQEKAHNQD LGLAGSCLAR FSTMPFLYCN PGDICHYASR 1560 NDKSYWLSTT APLPMMPVAE EEIRPYISRC SVCEAPAVAI AVHSQDVSIP HCPAGWRSLW 1620 IGYSFLMHTA AGDEGGGQSL VSPGSCLEDF RATPFIECNG ARGTCHYYAN KYSFWLTTIP 1680 EQSFQSSPSA DTLKAGLIRT HISRCQVCMK NL 1712 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A2 | A0A452G6J0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL4A2 | 1284 | P08572 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Col4a2 | 12827 | P08122 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | 452661 | K7C8W0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | F1RLL9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Col4a2 | F1M6Q3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005587 | collagen type IV trimer |
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0035987 | endodermal cell differentiation |
| GO:0030198 | extracellular matrix organization |
| GO:0016525 | negative regulation of angiogenesis |
| GO:0006351 | transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |