| Tag | Content |
|---|---|
| Uniprot ID | A0A452G725 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000032272 |
| Ensembl nucleotide ID | ENSCHIG00000026310 |
| Gene name | Frizzled class receptor 7 |
| Gene symbol | FZD7 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRGSCAAVSR LPLDLCTLVL ALLGALPAGA GAQPYHGEKG ISVPDHGFCQ PISIPLCTDI 60 AYNQTILPNL LGHTNQEEAG LEVHQFYPLV KVQCSPELRF FLCSMYAPVC TVLDKAIPPC 120 RSLCERARQG CEALMNKFGF QWPERLRCEN FPVHGAGEIC VGQNTSDGSG GAGGGPTAYP 180 TAPYLPDLPF TALPPGAADG RGRSAFPFSC PRQLKVPPYL GYRFLGERDC GAPCEPGRAN 240 GLMYFKEEER RFARLWVGVW SVLCCASTLF TVLTYLVDMR RFSYPERPII FLSGCYFMVA 300 VAHVAGFLLE DRAVCVERFS DDGYRTVAQG TKKEGCTILF MVLYFFGMAS SIWWVILSLT 360 WFLAAGMKWG HEAIEANSQY FHLAAWAVPA VKTITILAMG QVDGDLLSGV CYVGLSSVDA 420 LRGFVLAPLF VYLFIGTSFL LAGFVSLFRI RTIMKHDGTK TEKLEKLMVR IGVFSVLYTV 480 PATIVLACYF YEQAFREHWE RTWLLQTCKS YAVPCPPGHF PPMSPDFTVF MIKYLMTMIV 540 GITTGFWIWS GKTLQSWRRF YHRLSHSSKG ETADSNSFA 579 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD7 | 524255 | F1N4K7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | FZD7 | F6XX91 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | FZD7 | A0A452G725 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FZD7 | 8324 | O75084 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fzd7 | 14369 | Q61090 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FZD7 | 459881 | A0A2I3TGC6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FZD7 | F1SI18 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Fzd7 | 100360552 | D4ACM8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0043231 | intracellular membrane-bounded organelle |
| GO:0005886 | plasma membrane |
| GO:0055038 | recycling endosome membrane |
| GO:0005109 | frizzled binding |
| GO:0030165 | PDZ domain binding |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0060231 | mesenchymal to epithelial transition |
| GO:2000726 | negative regulation of cardiac muscle cell differentiation |
| GO:0010812 | negative regulation of cell-substrate adhesion |
| GO:0042666 | negative regulation of ectodermal cell fate specification |
| GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade |
| GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing |
| GO:0042327 | positive regulation of phosphorylation |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0060828 | regulation of canonical Wnt signaling pathway |
| GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration |
| GO:0048103 | somatic stem cell division |
| GO:0019827 | stem cell population maintenance |
| GO:0034446 | substrate adhesion-dependent cell spreading |
| GO:0033077 | T cell differentiation in thymus |