| Tag | Content |
|---|---|
| Uniprot ID | D4ACM8 |
| Entrez ID | 100360552 |
| Genbank protein ID | EDL98954.1 |
| Genbank nucleotide ID | NM_001271185.1 |
| Ensembl protein ID | ENSRNOP00000021569 |
| Ensembl nucleotide ID | ENSRNOG00000016119 |
| Gene name | Frizzled class receptor 7 |
| Gene symbol | Fzd7 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRGPGTEASH SPLGLCALVL ALLGALPTDT GAQPYHGEKG ISVPDHGFCQ PISIPLCTDI 60 AYNQTILPNL LGHTNQEDAG LEVHQFYPLV KVQCSPELRF FLCSMYAPVC TVLDQAIPPC 120 RSLCERARQG CEALMNKFGF QWPERLRCEN FPVHGAGEIC VGQNTSDGSG GAGGSPTAYP 180 TAPYLPDPPF TAMSPSDGRG RWSFPFSCPR QLKVPPYLGY RFLGERDCGA PCEPGRANGL 240 MYFKEEERRF ARLWVGVWSV LCCASTLFTV LTYLVDMRRF SYPERPIIFL SGCYFMVAVA 300 HVAGFLLEDR AVCVERFSDD GYRTVAQGTK KEGCTILFMV LYFFGMASSI WWVILSLTWF 360 LAAGMKWGHE AIEANSQYFH LAAWAVPAVK TITILAMGQV DGDLLSGVCY VGLSSVDALR 420 GFVLAPLFVY LFIGTSFLLA GFVSLFRIRT IMKHDGTKTE KLEKLMVRIG VFSVLYTVPA 480 TIVLACYFYE QAFREHWERT WLLQTCKSYA VPCPPGHFSP MSPDFTVFMI KYLMTMIVGI 540 TTGFWIWSGK TLQSWRRFYH RLSHSSKGET AV 572 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD7 | 524255 | F1N4K7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | FZD7 | F6XX91 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | FZD7 | A0A452G725 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FZD7 | 8324 | O75084 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fzd7 | 14369 | Q61090 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FZD7 | 459881 | A0A2I3TGC6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FZD7 | F1SI18 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Fzd7 | 100360552 | D4ACM8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0043231 | intracellular membrane-bounded organelle |
| GO:0005886 | plasma membrane |
| GO:0055038 | recycling endosome membrane |
| GO:0005109 | frizzled binding |
| GO:0030165 | PDZ domain binding |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0060231 | mesenchymal to epithelial transition |
| GO:2000726 | negative regulation of cardiac muscle cell differentiation |
| GO:0010812 | negative regulation of cell-substrate adhesion |
| GO:0042666 | negative regulation of ectodermal cell fate specification |
| GO:0035567 | non-canonical Wnt signaling pathway |
| GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade |
| GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing |
| GO:0042327 | positive regulation of phosphorylation |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0060828 | regulation of canonical Wnt signaling pathway |
| GO:0006355 | regulation of transcription, DNA-templated |
| GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration |
| GO:0048103 | somatic stem cell division |
| GO:0019827 | stem cell population maintenance |
| GO:0034446 | substrate adhesion-dependent cell spreading |
| GO:0033077 | T cell differentiation in thymus |