Gene: fgf8a

Basic information

Tag Content
Uniprot ID A2CF52
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000119341
Ensembl nucleotide ID ENSDARG00000003399
Gene name Fibroblast growth factor
Gene symbol fgf8a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRLIPSRLSY LFLHLFAFCY YAQHVSEQSK VTDRVSRRLI RTYQLYSRTS GKHVQVLANK 60
KINAMAEDGD VHAKLIVETD TFGSRVRIKG AETGFYICMN RRGKLIGKKN GLGKDCIFTE 120
IVLENNYTAL QNVKYEGWYM AFTRKGRPRK GSKTRQHQRE VHFMKRLPKG HQIAEHRPFD 180
FINYPFNRRT KRTRYSGER 199

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFGF8326284F1N6G8Bos taurusPredictionMore>>
1:1 orthologFGF8A0A452EXW2Capra hircusPredictionMore>>
1:1 orthologFGF82253P55075Homo sapiensPredictionMore>>
1:1 orthologFgf814179P37237CPO,CLPE13.5, E16.5Mus musculusPublicationMore>>
1:1 orthologFGF8H2Q2G4Pan troglodytesPredictionMore>>
1:1 orthologFGF8A0A287B086Sus scrofaPredictionMore>>
1:1 orthologFgf829349Q76LI5Rattus norvegicusPredictionMore>>
1:1 orthologfgf8aA2CF52Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005104 fibroblast growth factor receptor binding
GO:0008083 growth factor activity
GO:0008543 fibroblast growth factor receptor signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0339 Growth factor
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR028249 FGF8
IPR002209 Fibroblast_GF_fam
IPR008996 IL1/FGF

PROSITE

PROSITE ID PROSITE Term
PS00247 HBGF_FGF

Pfam

Pfam ID Pfam Term
PF00167 FGF