CleftGeneDB-Search

Gene: FGF8

Basic information

Tag	Content
Uniprot ID	F1N6G8
Entrez ID	326284
Genbank protein ID
Genbank nucleotide ID	NM_001206678.1
Ensembl protein ID	ENSBTAP00000002001
Ensembl nucleotide ID	ENSBTAG00000001530
Gene name	Fibroblast growth factor
Gene symbol	FGF8
Organism	Bos taurus
NCBI taxa ID	9913
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	MGSPRSALSC LLLHLLVLCL QAQEGPGGGP ALGRELASLF RAGRESQGVS QQVTVQSSPN 60 FTQHVREQSL VTDQLSRRLI RTYQLYSRTS GKHVQVLANK RINAMAEDGD PFAKLIVETD 120 TFGSRVRVRG AETGLYICMN KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM 180 AFTRKGRPRK GSKTRQHQRE VHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA 240 PEPR 244

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	Fgf8	14179	P37237	CPO,CLP	E13.5, E16.5	Mus musculus	Publication	More>>
1:1 ortholog	FGF8	326284	F1N6G8			Bos taurus	Prediction	More>>
1:1 ortholog	FGF8		A0A452EXW2			Capra hircus	Prediction	More>>
1:1 ortholog	FGF8	2253	P55075			Homo sapiens	Prediction	More>>
1:1 ortholog	FGF8		H2Q2G4			Pan troglodytes	Prediction	More>>
1:1 ortholog	FGF8		A0A287B086			Sus scrofa	Prediction	More>>
1:1 ortholog	Fgf8	29349	Q76LI5			Rattus norvegicus	Prediction	More>>
1:1 ortholog	fgf8a		A2CF52			Danio rerio	Prediction	More>>

Showing 1 to 8 of 8 entries

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Gene ontology

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GO ID	GO Term
GO:0000165	MAPK cascade
GO:0001569	branching involved in blood vessel morphogenesis
GO:0001656	metanephros development
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0001759	organ induction
GO:0001839	neural plate morphogenesis
GO:0001947	heart looping
GO:0001974	blood vessel remodeling
GO:0003148	outflow tract septum morphogenesis
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104	fibroblast growth factor receptor binding
GO:0005576	extracellular region
GO:0008078	mesodermal cell migration
GO:0008083	growth factor activity
GO:0008284	positive regulation of cell population proliferation
GO:0008406	gonad development
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0010628	positive regulation of gene expression
GO:0021543	pallium development
GO:0021544	subpallium development