| Tag | Content |
|---|---|
| Uniprot ID | A9JRW8 |
| Entrez ID | 100001615 |
| Genbank protein ID | AAI55826.1 |
| Genbank nucleotide ID | XM_005156536.3 |
| Ensembl protein ID | ENSDARP00000136805 |
| Ensembl nucleotide ID | ENSDARG00000056801 |
| Gene name | Suppressor of fused homolog |
| Gene symbol | sufu |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDEMRPSSGA AAHLGLASIF PPGLQAIYGE CRRLYPDQAN PLQVTAIVKY WLGGPDPLDY 60 ISMYRNVGCP GQDVPEHWHY VSLGLSDLYG DNRVHEFTGL EGPSGFGFEL TFRLKREAGE 120 TAPPTWPAEL MQGLARYVFQ SENTFCSGDH ISWHSPLDNS ESRIQHMLLT EDPQMHPVQT 180 PFGHVSFLQI VGVCTEELQA AQQWNGQGIL DLLRGVHIAG GPWLITDMRR GESIFDIDPH 240 LQQERVDKGI ETDGSNLSGV SAKCAWDDLS RPPEDEDDSR SICIGAQPRR LSDKDTEQIR 300 EALRKGLEIK SKSILPPISG QRHSHDRPQS RKDSLESESS AAIVPHELVR TRQLESVHLK 360 FNQESGTLIP MCLRGRLLHG RHFTFKSING DTAITFVSTG VEGAFATEEH PYAAHGPWLQ 420 ILLTEEFVEQ MLAEVQDLST RDVCKLPKEY SWPDKKLKIS VLPDTVFDSP LQ 472 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SUFU | 608531 | E2RAI7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SUFU | 102181468 | A0A452FM19 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SUFU | 51684 | Q9UMX1 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sufu | 24069 | Q9Z0P7 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SUFU | 450699 | A0A2I3RQE6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SUFU | 100345361 | U3KN20 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Sufu | 361769 | Q4V8C6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sufu | 100001615 | A9JRW8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0035301 | Hedgehog signaling complex |
| GO:0005634 | nucleus |
| GO:0008134 | transcription factor binding |
| GO:0008270 | zinc ion binding |
| GO:0042994 | cytoplasmic sequestering of transcription factor |
| GO:0033333 | fin development |
| GO:0030097 | hemopoiesis |
| GO:0002088 | lens development in camera-type eye |
| GO:0045879 | negative regulation of smoothened signaling pathway |
| GO:0007224 | smoothened signaling pathway |