| Tag | Content |
|---|---|
| Uniprot ID | B2LT56 |
| Entrez ID | |
| Genbank protein ID | ACC59092.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000155804; ENSDARP00000154079; |
| Ensembl nucleotide ID | ENSDARG00000116608 |
| Gene name | Homeobox protein |
| Gene symbol | pitx1 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNVDMASSFH LPRSASSTRE TLENTSSESS DTEAAEKERS VEQRSDDGNA DDPKKKKQRR 60 QRTHFTSQQL QELEATFQRN RYPDMSTREE IAVWTNLTEA RVRVWFKNRR AKWRKRERNQ 120 QMDLCKNSYL PQFSGLMQPY DDVYPTYTYN NWTNKGLTPA PLSTKNFTFF NSMSPLTSQS 180 MFSAPSSISS MSMASGMGHS AVPGMPTTGL NNIGNLNGIG GSTINPAMSS STCPYGPPGS 240 PYSVYRDTCN SSLATLRLKS KQHPSFGYSG LQSPGSSLNA CQYNS 285 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PITX1 | 508754 | F1MU46 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PITX1 | 481513 | E2RRG5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PITX1 | 102181864 | A0A452DRM8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PITX1 | 5307 | P78337 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pitx1 | 18740 | P70314 | CPO | E12.5, E13.5, E14.5, E15.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PITX1 | 462072 | A0A2J8LRP3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PITX1 | 100689266 | F8SIP6 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Pitx1 | 113983 | Q99NA7 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pitx1 | B2LT56 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0009653 | anatomical structure morphogenesis |
| GO:0007275 | multicellular organism development |
| GO:0006357 | regulation of transcription by RNA polymerase II |