Gene: hoxa2b

Basic information

Tag Content
Uniprot ID B3DG99
Entrez ID
Genbank protein ID AAI62323.1
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000023072
Ensembl nucleotide ID ENSDARG00000023031
Gene name Homeo box A2b
Gene symbol hoxa2b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MNYEFERETG FINSQPSLAE CLTSFPPVGD AFQSSSIKSS TLSHSTLIPP PFEQTIPSLN 60
PGSHPRHSRP KQNPNGSCPL PAASLPPEYP WMKEKKASKK NQTTSTAATT DPGPLYFSPQ 120
GSPEISDGGS GATRRLRTAY TNTQLLELEK EFHFNKYLCR PRRVEIAALL DLTERQVKVW 180
FQNRRMKHKR QTQCKENHHG DGKPPSLEEA GGRGDGKSFF EQVANNVSGA LLEREGYPFQ 240
QNTLTSQQSQ NGHNSDSQSA TVSPLGSNDK HLKHFPNPSP TVPICTTTMA PDCASAQNNG 300
SPSALDVSLQ DFNVFSNDSC LHLSDAVSPS LSESVDSPIG LTTEAFDFFS ETLTTIDLQH 360
LSY 363

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHOXA2F1MD21Bos taurusPredictionMore>>
1:1 orthologHOXA2609592E2R5Y1Canis lupus familiarisPredictionMore>>
1:1 orthologHOXA2102172597A0A452FXW8Capra hircusPredictionMore>>
1:1 orthologHOXA23199O43364Homo sapiensPredictionMore>>
1:1 orthologHoxa215399P31245CPOE12.5, E14.0, E13.5, E14.5, E15.0, E15.5Mus musculusPublicationMore>>
1:1 orthologHOXA2100519993F1SHT0Sus scrofaPredictionMore>>
1:1 orthologHoxa2108348165G3V6R6Rattus norvegicusPredictionMore>>
1:1 orthologhoxa2bB3DG99Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0007275 multicellular organism development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa

PROSITE

PROSITE ID PROSITE Term
PS00032 ANTENNAPEDIA
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain