| Tag | Content |
|---|---|
| Uniprot ID | B4F7B6 |
| Entrez ID | 307151 |
| Genbank protein ID | AAI68209.1; EDL78772.1; |
| Genbank nucleotide ID | XM_017600573.1; NM_001107368.2; |
| Ensembl protein ID | ENSRNOP00000059998 |
| Ensembl nucleotide ID | ENSRNOG00000016585 |
| Gene name | BMI1 proto-oncogene, polycomb ring finger |
| Gene symbol | Bmi1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MHRTTRIKIT ELNPHLMCVL CGGYFIDATT IIECLHSFCK TCIVRYLETS KYCPICDVQV 60 HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120 DRRVIADDEI ISLSIEFFHP SRSDRKVTKE KPKEEVNDKR YLRCPAALTV MHLRKFLRSK 180 MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK RMKMSQQRDG 240 LTAAGELESD SGSDKANSPA GGAPSTSSCL PSPSTPVQSP HPQFPHISST MNGTSNSPSG 300 NHQSSFASRP RKSSVNGSSA TSSG 324 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BMI1 | 510666 | Q32KX7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | COMMD3 | 487097 | E2RTM4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | BMI1 | 102191809 | A0A452EWQ5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | COMMD3-BMI1 | 100532731 | R4GMX3 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bmi1 | 12151 | P25916 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | BMI1 | 466023 | A0A2I3SRC0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BMI1 | A0A287A130 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BMI1 | 100009347 | G1SNW4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bmi1 | 307151 | B4F7B6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0000792 | heterochromatin |
| GO:0016604 | nuclear body |
| GO:0005634 | nucleus |
| GO:0031519 | PcG protein complex |
| GO:0035102 | PRC1 complex |
| GO:0000151 | ubiquitin ligase complex |
| GO:0003682 | chromatin binding |
| GO:1990841 | promoter-specific chromatin binding |
| GO:0071535 | RING-like zinc finger domain binding |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0097027 | ubiquitin-protein transferase activator activity |
| GO:0008270 | zinc ion binding |
| GO:0007420 | brain development |
| GO:0071549 | cellular response to dexamethasone stimulus |
| GO:0071347 | cellular response to interleukin-1 |
| GO:0006342 | chromatin silencing |
| GO:0006306 | DNA methylation |
| GO:0048706 | embryonic skeletal system development |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0030097 | hemopoiesis |
| GO:0016573 | histone acetylation |
| GO:0036353 | histone H2A-K119 monoubiquitination |
| GO:0016574 | histone ubiquitination |
| GO:0006959 | humoral immune response |
| GO:0001701 | in utero embryonic development |
| GO:2001234 | negative regulation of apoptotic signaling pathway |
| GO:0045814 | negative regulation of gene expression, epigenetic |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0030890 | positive regulation of B cell proliferation |
| GO:0048146 | positive regulation of fibroblast proliferation |
| GO:0033092 | positive regulation of immature T cell proliferation in thymus |
| GO:0051443 | positive regulation of ubiquitin-protein transferase activity |
| GO:2000011 | regulation of adaxial/abaxial pattern formation |
| GO:0010468 | regulation of gene expression |
| GO:0021903 | rostrocaudal neural tube patterning |
| GO:0001501 | skeletal system development |
| GO:0048103 | somatic stem cell division |
| Pfam ID | Pfam Term |
|---|---|
| PF16207 | RAWUL |