| Tag | Content |
|---|---|
| Uniprot ID | B8JLK8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000044313 |
| Ensembl nucleotide ID | ENSDARG00000006314 |
| Gene name | Integrin, alpha V |
| Gene symbol | itgav |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGKHFVRYWL WALVALFTTK RAPAFNLDIS KPTVFSGPPG SYFGFSVAFF NPDNSQLNIL 60 VGAPRANTSD QTPSAVTERG AVFSCPWQKS GTCTQIQFDS TDDRKHSNGQ QMEFKSNQWF 120 GATVRSSGDQ ILACAPLYQW STYGFSEREP VGTCYLKKGN NIVEYSPCRS KSNSPEGQGF 180 CQAGFSADFV KKNRVVIGGP GSFYWQGQLI SDDVTEVINR YNKEFLTPYS NQLSTKPAGA 240 QYDDSYLGYS VAVGDFNEDG EDDYVTGVPR GEKALGYVNI FNGRNMESMY NFTGTQMAAY 300 FGHSVAAVDV NNDGKMDLFV GAPLFMDRGS DGKLREVGQV YVYLGKGGFT FNSVIKLTGS 360 EIYARYGSSV CSVGDLNMDG YNDVAIAAPY GGPFHRGLVY IHNGRSTGPN PVASQVLEGT 420 WASVSMPSSF GYSMNGGTDV DQNGYPDLIV GAFGADKAIL YRARPVISVN TTLDISPQIL 480 NPEDKSCTLP STATKVSCFT VKYCLKASGK GAPSSLLFQV DLTLDRLKHK GAIKRVLFLY 540 NKMSHYSKNM TVNNNQGLAC EELQAYLIDD SEFRDKITPI SVFMEYSLDF KSAADKTGLL 600 PILDQSAPTN VTKQAHILLD CGEDNICKPD LKLSVVSDQN EIYIGDDNPL TLEVTAENGG 660 EGAYEADLIV TLPSQADFTA VVRNSETLSR LSCAFKKDNQ TRVVVCDLGN PMKGGTKIVA 720 GLRFSVHQLS EQDTEVKFGL QIQSTNQFNN TSNLVSVVTK LAVLAKVELR GVSAPEQVFL 780 PIANWQPKEN PVLEDDIGPL VQHIYELRNK GPSTFSKAIL DVQWPYRFNN GSLLYITKFS 840 VDGNMNCSSN RELNPLNVTS PRFLDQNDTS ASGAEGRNRH NVHRRDLEEK HGEENLEILD 900 CGNAECQEIK CFVGRLEKGQ SAILFIYSRL AVNTFLKAES QNKSYIVRSS ASFSVIEMPY 960 KNLNPELPTS TQSASLKVIW NSENPQPVPG WVVALAVLAG LLLLALLIFV MYKLGFFNRV 1020 RPPQEDRTEK EQLQPQENGD RNTEA 1045 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGAV | 281875 | A0A3Q1MXS2 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGAV | A0A452E162 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ITGAV | 3685 | P06756 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgav | 16410 | P43406 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGAV | A0A2I3SM65 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ITGAV | F1RYJ4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ITGAV | 100008956 | A0A5F9D0E2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Itgav | A0A0G2JVZ6 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | itgav | B8JLK8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0008305 | integrin complex |
| GO:0001525 | angiogenesis |
| GO:0090245 | axis elongation involved in somitogenesis |
| GO:0001568 | blood vessel development |
| GO:0007155 | cell adhesion |
| GO:0016477 | cell migration |
| GO:0042074 | cell migration involved in gastrulation |
| GO:0001935 | endothelial cell proliferation |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0070121 | Kupffer's vesicle development |