Gene: ITGAV

Basic information

Tag Content
Uniprot ID F1RYJ4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000016982
Ensembl nucleotide ID ENSSSCG00000016027
Gene name Integrin subunit alpha V
Gene symbol ITGAV
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLHADQADRV LLGGPGSFYW QGQLISDQVA EIVSKYDPKV YSIKYNNQLA TRTAQAIFDD 60
SYLGYSVAVG DFNGDGIDDF VSGVPRAART LGMVYIYDGK NMSSLHNFTG EQMAAYFGFS 120
VAATDINGDD YADVFIGAPL FMDRGSDGKL QEVGQVSVSL QKASGNFQTT KLNGFEVFAR 180
FGSAIAPLGD LDQDGFNDIA IAAPYGGEDK KGIVYIFNGR PTGLNAVPSQ ILEGKWAARS 240
MPPSFGYSMK GATDIDKNGY PDLIVGAFGV DRAVLYRARP VITVNAGLEV YPSILNQDNK 300
TCPLPGTDLK VSCFHVRFCL KADGKGTLPT KLNFQVELLL DKLKQKGAIR RALFLHNRFP 360
GHSKNMTISR GGQMQCEELI AYLRDESEFR DKLTPITIFM EYRLDYTTAA DVTGLQPILN 420
QFTPANISRQ AHILLDCGED NVCKPKLEVS VDSDQKKIYV GDDNPLTLIV KAQNQGEGAY 480
EAELIVSIPP QADFIGVVRN SEALARLSCA FKTENQTRQV VCDLGNPMKA GTQLLAGLRF 540
SVQQQSEMDT SVKFDLQIQS SNLFDKVSPV VSYKVDLAVL AAVEIRGVSS PDHIFLPIPN 600
WEHKENPETE EDVGPVVQHI YELRNNGPSS FSKAMLNLQW PYKYNNNTLL YILQYDIDGP 660
MNCTSDMEIN PLRIKTEKND TVGGQGDRNH LVTKRDLTLI EGDVHTLGCG IAECLKIVCQ 720
VGRLDRGKSA ILYVKSLLWT ETFMNKENQN HSYSLKSSAS FNVIEFPYKN LPIEDIFNST 780
LVTTNVTWGI QPAPMPVPVW VIILAVLAGL LLLAVLVFVM YRMGFFKRVR PPQEEQEREQ 840
LQPHENGEGN SET 853

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologITGAV281875A0A3Q1MXS2Bos taurusPredictionMore>>
1:1 orthologITGAVA0A452E162Capra hircusPredictionMore>>
1:1 orthologITGAV3685P06756Homo sapiensPredictionMore>>
1:1 orthologItgav16410P43406CPOMus musculusPublicationMore>>
1:1 orthologITGAVA0A2I3SM65Pan troglodytesPredictionMore>>
1:1 orthologITGAVF1RYJ4Sus scrofaPredictionMore>>
1:1 orthologITGAV100008956A0A5F9D0E2Oryctolagus cuniculusPredictionMore>>
1:1 orthologItgavA0A0G2JVZ6Rattus norvegicusPredictionMore>>
1:1 orthologitgavB8JLK8Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0008305 integrin complex
GO:0007155 cell adhesion
GO:0007229 integrin-mediated signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0130 Cell adhesion
KW-0401 Integrin
KW-0472 Membrane
KW-1267 Proteomics identification
KW-0675 Receptor
KW-1185 Reference proteome
KW-0677 Repeat
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013517 FG-GAP
IPR013519 Int_alpha_beta-p
IPR000413 Integrin_alpha
IPR013649 Integrin_alpha-2
IPR018184 Integrin_alpha_C_CS
IPR028994 Integrin_alpha_N
IPR032695 Integrin_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS51470 FG_GAP
PS00242 INTEGRIN_ALPHA

Pfam

Pfam ID Pfam Term
PF01839 FG-GAP
PF00357 Integrin_alpha
PF08441 Integrin_alpha2