| Tag | Content |
|---|---|
| Uniprot ID | D3ZM81 |
| Entrez ID | 108348320 |
| Genbank protein ID | EDL88160.1 |
| Genbank nucleotide ID | XM_008773712.2; XM_006236526.3; XM_006224929.2; XM_006257707.2; XM_006224928.3; XM_008762939.2; XM_006236527.2; XM_008775738.2; XM_006257706.3; |
| Ensembl protein ID | ENSRNOP00000008447; ENSRNOP00000072327; |
| Ensembl nucleotide ID | ENSRNOG00000061608; ENSRNOG00000006281; |
| Gene name | Homeobox protein Hox-A3 |
| Gene symbol | Hoxa3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQKATYYDSS AIYGGYPYQA ANGFAYNASQ QPYAPSATLG TDGVEYHRPA CSLQSPASAG 60 AHPKSHELSE ACLRTLSGPP SQPPGLGDPP LPPPPPQAAP PAPQPPQPPP QPPAPTPAAP 120 PPPSSVSPPQ SANSNPTPAS TAKSPLLNSP TVGKQIFPWM KESRQNTKQK TSGSSSGESC 180 AGDKSPPGQA SSKRARTAYT SAQLVELEKE FHFNRYLCRP RRVEMANLLN LTERQIKIWF 240 QNRRMKYKKD QKGKGMLTSS GGQSPSRSPV PPGAGGYLNS MHSLVNSVPY EPQSPPPFSK 300 PPQGAYGLPP ASYPAPLPSC APPPPPQKRY TAAGSGAGGT PEYDPHAHGL QGNGSYGTPH 360 LQGSPVFVGG SYVEPMGNSG PALFGLTHLP HTTSAAVDYG GSGPLGSGHH HGPGPGEPHP 420 TYTDLTAHHP SQGRIQEAPK LTHL 444 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HOXA3 | 509991 | Q08DG7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | HOXA3 | 482368 | J9NWE8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HOXA3 | A0A452EKL1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | HOXA3 | 3200 | O43365 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hoxa3 | 15400 | P02831 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HOXA3 | 100519809 | F1SHT1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Hoxa3 | 108348320 | D3ZM81 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | hoxa3a | 58049 | Q8AWZ2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0071837 | HMG box domain binding |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0001525 | angiogenesis |
| GO:0048645 | animal organ formation |
| GO:0009887 | animal organ morphogenesis |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0001974 | blood vessel remodeling |
| GO:0051216 | cartilage development |
| GO:0048706 | embryonic skeletal system development |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0010467 | gene expression |
| GO:0021615 | glossopharyngeal nerve morphogenesis |
| GO:0060017 | parathyroid gland development |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:1900122 | positive regulation of receptor binding |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0010159 | specification of animal organ position |
| GO:0048538 | thymus development |
| GO:0030878 | thyroid gland development |