| Tag | Content |
|---|---|
| Uniprot ID | Q8AWZ2; Q1L969; Q4PRB1; Q9YGT7; |
| Entrez ID | 58049 |
| Genbank protein ID | AAD15938.1; CAK10851.1; AAH76469.1; CAD52134.1; AAY67910.1; |
| Genbank nucleotide ID | NM_131534.1 |
| Ensembl protein ID | ENSDARP00000152675; ENSDARP00000139302; ENSDARP00000152861; ENSDARP00000130226; |
| Ensembl nucleotide ID | ENSDARG00000103862 |
| Gene name | Homeobox protein Hox-A3a |
| Gene symbol | hoxa3a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Sequence | MQKATYCDGS AIYSGLPYQS ANGLGYDASQ QQYLQALHAE SEYHRPACSL QSPGISAGLH 60 TSNEMSEVCQ QINGTQATVT DTSDNKQPPT APSGPSSPSS LNQIPNIDSA AKNPVHVSPT 120 PSTRKHIFPW MKESRQNTKQ KSCSIISVES CAGDKSPPGS AASKRARTAY TSAQLVELEK 180 EFHFNRYLCR PRRVEMANLL NLTERQIKIW FQNRRMKYKK DQKGLGMMPS PGAQSPHSPV 240 SLSSGGGGGG GSAYLSSMHS LVNSVTYDSP SPASYNKPQS NTYSLPTSYP PLNNCPPPQK 300 RYQGTGTATP EYDTHHIQGN NNYGTQVQGS PVYVSGGGGY SDSLVGMGAS VFGLTHLPHP 360 SQGNIDYNGA ITMGNSHQQG ACDSNPCTFT DLTPHYSQGR IQEAPKLTHL |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HOXA3 | 509991 | Q08DG7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | HOXA3 | 482368 | J9NWE8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HOXA3 | A0A452EKL1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | HOXA3 | 3200 | O43365 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hoxa3 | 15400 | P02831 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HOXA3 | 100519809 | F1SHT1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Hoxa3 | 108348320 | D3ZM81 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | hoxa3a | 58049 | Q8AWZ2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003677 | DNA binding |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0006357 | regulation of transcription by RNA polymerase II |