| Tag | Content |
|---|---|
| Uniprot ID | D3ZQF8 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000025913 |
| Ensembl nucleotide ID | ENSRNOG00000043416 |
| Gene name | BCL3, transcription coactivator |
| Gene symbol | Bcl3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPMYSTPTMA PPFPLLNLPT HPYSMICPVE HPLSADIAMA TRVDEDGDTP LHIAVVQNNK 60 TAVYRILSLF KLGNREVDVH NNLRQTPLHL AVITTLPDIV RLLVTAGASP MALDRHGQTA 120 VHLACEHRSP SCLQALLDSA TPGSVDLEAR NYEGLTALHV AVNTGCQEAV LLLLERGADI 180 DAVDIKSGRS PLIHAVENNS LNMVQLLLLH GANVNAQMYS GSSALHSASG RGLLPLVRTL 240 VRSGADSGLK NCHNDTPLMV ARSRRVIDIL RGKASRAASG SQPDPSPDQS ATNSPESSSR 300 LSSNGLQSSP SSSPSLSPPK DAPSFPMTPQ NYFLPATSAP AFLPFPGVLR GPGRPVAPSP 360 APGSS 365 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BCL3 | 531942 | E1BCE6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | 102188215 | A0A452EUS0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | 602 | P20749 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Bcl3 | 12051 | Q9Z2F6 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | K7DP79 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Bcl3 | D3ZQF8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0032996 | Bcl3-Bcl10 complex |
| GO:0033257 | Bcl3/NF-kappaB2 complex |
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0030496 | midbody |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0032991 | protein-containing complex |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:0019730 | antimicrobial humoral response |
| GO:0006974 | cellular response to DNA damage stimulus |
| GO:0042742 | defense response to bacterium |
| GO:0042832 | defense response to protozoan |
| GO:0030330 | DNA damage response, signal transduction by p53 class mediator |
| GO:0030198 | extracellular matrix organization |
| GO:0002268 | follicular dendritic cell differentiation |
| GO:0002467 | germinal center formation |
| GO:0002455 | humoral immune response mediated by circulating immunoglobulin |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling |
| GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| GO:0002315 | marginal zone B cell differentiation |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0045415 | negative regulation of interleukin-8 biosynthetic process |
| GO:0046426 | negative regulation of receptor signaling pathway via JAK-STAT |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process |
| GO:0032729 | positive regulation of interferon-gamma production |
| GO:0045082 | positive regulation of interleukin-10 biosynthetic process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0045727 | positive regulation of translation |
| GO:0042981 | regulation of apoptotic process |
| GO:0051101 | regulation of DNA binding |
| GO:1901222 | regulation of NIK/NF-kappaB signaling |
| GO:0010225 | response to UV-C |
| GO:0009615 | response to virus |
| GO:0048536 | spleen development |
| GO:0042088 | T-helper 1 type immune response |
| GO:0045064 | T-helper 2 cell differentiation |
| GO:0006351 | transcription, DNA-templated |