| Tag | Content |
|---|---|
| Uniprot ID | K7DP79; A0A2J8PYA2; H2R609; |
| Entrez ID | |
| Genbank protein ID | JAA24541.1; JAA07585.1; JAA42825.1; JAA16289.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000048640 |
| Ensembl nucleotide ID | ENSPTRG00000011122 |
| Gene name | B-cell CLL/lymphoma 3 |
| Gene symbol | BCL3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPRCPAGAMD EGPVDLRTRP KAAGLPGAAL PLRKRPLRAP SPEPAAPRGA AGLVVPLDPL 60 RGGCDLPAVP GPPHGLARPE ALYYPGALLP LYPTRAMGSP FPLVNLPTPL YPMMCPMEHP 120 LSADIAMATR ADEDGDTPLH IAVVQGNLPA VHRLVNLFQQ GGRELDIYNN LRQTPLHLAV 180 ITTLPSVVRL LVTAGASPMA LDRHGQTAAH LACEHRSPTC LRALLDSAAP GTLDLEARNY 240 DGLTALHVAV NTECQETVQL LLERGADIDA VDIKSGRSPL IHAVENNSLS MVQLLLQHGA 300 NVNAQMYSGS SALHSASGRG LLPLVRTLVR SGADSSLKNC HNDTPLMVAR SRRVIDILRG 360 KATRPASTSQ PDPSPDRSAN TSPESSSRLS SNGLLSTSPS SSPSQSPPRD PPGFPMAPPN 420 FFLPSPSPPT FLPFAGVLRG PGRPVPPSPA PGGS 454 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BCL3 | 531942 | E1BCE6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | 102188215 | A0A452EUS0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | 602 | P20749 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Bcl3 | 12051 | Q9Z2F6 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BCL3 | K7DP79 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Bcl3 | D3ZQF8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0032996 | Bcl3-Bcl10 complex |
| GO:0033257 | Bcl3/NF-kappaB2 complex |
| GO:0005829 | cytosol |
| GO:0030496 | midbody |
| GO:0005654 | nucleoplasm |
| GO:0005886 | plasma membrane |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0008134 | transcription factor binding |
| GO:0019730 | antimicrobial humoral response |
| GO:0042742 | defense response to bacterium |
| GO:0042832 | defense response to protozoan |
| GO:0030330 | DNA damage response, signal transduction by p53 class mediator |
| GO:0030198 | extracellular matrix organization |
| GO:0002268 | follicular dendritic cell differentiation |
| GO:0002467 | germinal center formation |
| GO:0002455 | humoral immune response mediated by circulating immunoglobulin |
| GO:0007249 | I-kappaB kinase/NF-kappaB signaling |
| GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator |
| GO:0002315 | marginal zone B cell differentiation |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0045415 | negative regulation of interleukin-8 biosynthetic process |
| GO:0046426 | negative regulation of receptor signaling pathway via JAK-STAT |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process |
| GO:0032729 | positive regulation of interferon-gamma production |
| GO:0045082 | positive regulation of interleukin-10 biosynthetic process |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0045727 | positive regulation of translation |
| GO:0051101 | regulation of DNA binding |
| GO:1901222 | regulation of NIK/NF-kappaB signaling |
| GO:0010225 | response to UV-C |
| GO:0009615 | response to virus |
| GO:0048536 | spleen development |
| GO:0042088 | T-helper 1 type immune response |
| GO:0045064 | T-helper 2 cell differentiation |
| GO:0006351 | transcription, DNA-templated |
| Pfam ID | Pfam Term |
|---|---|
| PF12796 | Ank_2 |