| Tag | Content |
|---|---|
| Uniprot ID | D3ZY51 |
| Entrez ID | 304822 |
| Genbank protein ID | EDM09674.1 |
| Genbank nucleotide ID | NM_001107181.1 |
| Ensembl protein ID | ENSRNOP00000013532 |
| Ensembl nucleotide ID | ENSRNOG00000010076 |
| Gene name | Plakophilin 1 |
| Gene symbol | Pkp1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MNHSPLKTAL AYECFQDQDN STLALPSDQK MKTGTSGRQR VQEQVMMTVK RQKSKSSQSS 60 TLSHSNRGSM YDGLVDNYNN YGTTSRSSYF SKFQAGNGSW GYPIYNGTLK REPDNRRFSS 120 YSQMENWSRH YPRGSCATTG AGSDICFMQK IKASRSEPDL YCDPRGTLRK GTLGGKGQKT 180 TQNRYSFYST CSGQKAVKKC PVRPPSCTSK QDPVCMPPIS CNKDMSFGHS RASSKICSED 240 IECSGLTIPK AVQYLCSQDE KYQAIGAYYI QHTCFQDESA KQQVYQLGGI CKLVDLLRSP 300 NQNVQQAAAG ALRNLVFRST TNKLETRRQN GIREAVSLLR RSGSTEIQKQ LTGLLWNLSS 360 TDELKEELVA DALPVLTDRV IIPFSGWCDG NSNMSREVVD PEVFFNATGC LRNLSSADAG 420 RQTMRNYSGL IDSLMAYVQN CVAASRCDDK SVENCMCILH NLSYRLDAEV PTRYRQLEYN 480 TRNAYTEKSS TGCFSNRGDK MMNNNYDCPL PEEETNPKGS SWLYHSDAIR TYLNLMGKSK 540 KDATLEACAG ALQNLTASKG LMSNGMSQLI GIKEKGLPQI ARLLQSGNSD VVRESGVPRG 600 NQTPH 605 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PKP1 | A0A452FUQ9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PKP1 | 5317 | Q13835 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Pkp1 | 18772 | P97350 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | PKP1 | A0A2J8KHS3 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PKP1 | I3LGN8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pkp1 | 304822 | D3ZY51 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pkp1b | 797838 | E7FBR0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005912 | adherens junction |
| GO:0005911 | cell-cell junction |
| GO:0005737 | cytoplasm |
| GO:0030057 | desmosome |
| GO:1990124 | messenger ribonucleoprotein complex |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005886 | plasma membrane |
| GO:0045296 | cadherin binding |
| GO:0005521 | lamin binding |
| GO:0098609 | cell-cell adhesion |
| GO:0007043 | cell-cell junction assembly |
| GO:0045110 | intermediate filament bundle assembly |
| GO:1902373 | negative regulation of mRNA catabolic process |
| GO:0010628 | positive regulation of gene expression |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50176 | ARM_REPEAT |
| Pfam ID | Pfam Term |
|---|---|
| PF00514 | Arm |