Gene: PKP1

Basic information

Tag Content
Uniprot ID I3LGN8
Entrez ID
Genbank protein ID HCZ89944.1
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000033883
Ensembl nucleotide ID ENSSSCG00000030694
Gene name Plakophilin 1
Gene symbol PKP1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MNHSPLKTAL AYECFQDQDN STLALPSDQK MKTGTSGRQR VQEQVMMTVR RQKSKSSQSS 60
TLSHSNRGSL YDGLADNYNN YGTASRGSYY TKFQAGNGSW GYPIYNGTLK READNRRFSS 120
YSQMESWGRN YPRSGCHAPG AGSDICFMQK IKASRSEPDL YCDPRGTLRK GTLSSKGHKT 180
TQNRYSFYST CSGQKAVKKY PVCPPSCTPK PDPVYIPPVS CSKDLSFNHS RASSKICSED 240
IECSGLTIPK AVQYLSSQDE KCQAIGAYYI QHTCFQDESA KQQVYQLGGI CKLVELLRSP 300
NQNVQQAAAG ALRNLVFRST TNKLETRRQN GIREAVSLLG RTRSTEIQKQ LTGLLWNLSS 360
TDELKEELIA DALPVLADRV IIPFSGWRDG NSNLSRDTVD PEVFFNATGC LRNLSSADAG 420
RQTMRNYTGL IDSLMAYVQN CVAASRCDDK SVENCMCILH NLSYRLDAEV PTRYRQLDYN 480
ARNTYTEKSS TGCFSNKSDR MMNNNYDCPL PEEEPNPKGS SWLYHSDAIR TYLNLMGKSK 540
KDATLEACAG ALQNLTASKG LMSSGMSQLI GLKEKGLPQI ARLLQSGNSD VVRSGASLLS 600
NMSRHPVLHR VMGNQVFPEV TRLLTSHTGN TSNSEDILSS ACYTVRNLMA SQPQMAKQYF 660
SSNMINNVIN LCRSSASPKA AEAARLLLSD MWSSKELQGV LRQQGFDRNM LGAFPGANTF 720
RNFTSRF 727

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPKP1A0A452FUQ9Capra hircusPredictionMore>>
1:1 orthologPKP15317Q13835Homo sapiensPublicationMore>>
1:1 orthologPkp118772P97350Mus musculusPredictionMore>>
1:1 orthologPKP1A0A2J8KHS3Pan troglodytesPredictionMore>>
1:1 orthologPKP1I3LGN8Sus scrofaPredictionMore>>
1:1 orthologPkp1304822D3ZY51Rattus norvegicusPredictionMore>>
1:1 orthologpkp1b797838E7FBR0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005912 adherens junction
GO:0005911 cell-cell junction
GO:0005737 cytoplasm
GO:0030057 desmosome
GO:1990124 messenger ribonucleoprotein complex
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0045296 cadherin binding
GO:0005521 lamin binding
GO:0098609 cell-cell adhesion
GO:0007043 cell-cell junction assembly
GO:0045110 intermediate filament bundle assembly
GO:1902373 negative regulation of mRNA catabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR028432 Plakophilin-1
IPR028435 Plakophilin/d_Catenin

PROSITE

PROSITE ID PROSITE Term
PS50176 ARM_REPEAT

Pfam

Pfam ID Pfam Term
PF00514 Arm