| Tag | Content |
|---|---|
| Uniprot ID | E2R311 |
| Entrez ID | 479107 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_536254.5; XM_005618617.2; |
| Ensembl protein ID | ENSCAFP00000023536 |
| Ensembl nucleotide ID | ENSCAFG00000015978 |
| Gene name | UDP-glucose 6-dehydrogenase |
| Gene symbol | UGDH |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. |
| Sequence | MFEIKKICCI GAGYVGGPTC SVIAHMCPEI RVTVVDVNES RINAWNSPTL PIYEPGLKEV 60 VESCRGKNLF FSTNIDDAIK EADLVFISVN TPTKTYGMGK GRAADLKYIE ACARRIVQNS 120 HGYKIVTEKS TVPVRAAESI RRIFDANTKP NLNLQVLSNP EFLAEGTAIK DLKNPDRVLI 180 GGDETPEGQR AVQALCAVYE HWVPREKILT TNTWSSELSK LAANAFLAQR ISSINSISAL 240 CEATGADVEE VATAIGMDQR IGNKFLKASV GFGGSCFQKD VLNLVYLCEA LNLPEVARYW 300 QQVIDMNDYQ RRRFASRIID SLFNTVTDKK IAILGFAFKK DTGDTRESSS IYISKYLMDE 360 GAHLHIYDPK VPREQIVVDL SHPGVSQDDQ VSRLVTISKD PYEACDGAHA VVICTEWDMF 420 KELDYERIHK KMLKPAFIFD GRRVLDGLHN ELQTIGFQIE TIGKKVSSKR IPYAPSGEIP 480 KFSLQDPPNK KPRV 494 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | UGDH | 281564 | P12378 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | UGDH | 479107 | E2R311 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | UGDH | 102171772 | A0A452G134 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | UGDH | 7358 | O60701 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ugdh | 22235 | O70475 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | UGDH | 471171 | H2QPC9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | UGDH | 100627727 | I3LIM2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Ugdh | G3V6C4 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | ugdh | 116991 | A8WGP7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0051287 | NAD binding |
| GO:0003979 | UDP-glucose 6-dehydrogenase activity |
| GO:0030206 | chondroitin sulfate biosynthetic process |
| GO:0001702 | gastrulation with mouth forming second |
| GO:0006024 | glycosaminoglycan biosynthetic process |
| GO:0015012 | heparan sulfate proteoglycan biosynthetic process |
| GO:0034214 | protein hexamerization |
| GO:0006065 | UDP-glucuronate biosynthetic process |