Gene: Kif2a

Basic information

Tag Content
Uniprot ID F1M8L1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000019189
Ensembl nucleotide ID ENSRNOG00000014000
Gene name Kinesin-like protein
Gene symbol Kif2a
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATANFGKIQ IGIYVEIKRS DGRIHQAMVT SLNEDNESVT VEWIENGDTK GKEIDLESIF 60
SLNPDLVPDE DIEPSPEIPP PSSSSKVNKI VKNRRTVASI KNDPPPRDNR VVGSARARPS 120
QLPEQSSSAQ QNGSVSDISP VQAAKKEFGP PSRRKSNCVK EVEKLQEKRE KRRLQQQELR 180
EKRAQDVDAT NPNYEIMCMI RDFRGSLDYR PLTTADPIDE HRICVCVRKR PLNKKETQMK 240
DLDVITIPSK DVVMVHEPKQ KVDLTRYLEN QTFRFDYAFD DSAPNEMVYR FTARPLVETI 300
ERGMATCFAY GQTGSGKTHT MGGDFSGKNQ DCSKGIYALA ARDVFLMLKK PNYKKLELQV 360
YATFFEIYSG KVFDLLNRKT KLRVLEDGKQ QVQVVGLQER EVKCVEDVLK LIDIGNSCRT 420
SGQTSANAHS SRSHAVFQII LRRKGKLHGK FSLIDLAGNE RGADTSSADR QTRLEGAEIN 480
KSLLALKECI RALGRNKPHT PFRASKLTQV LRDSFIGENS RTCMIATISP GMASCENTLN 540
TLRYANRVKE LTVDPTAAGD VRPIMHHPPS QIDDLETQWG VGSSPQRDDL KLLCEQNEEE 600
VSPQLFTFHE AVSQMVEMEE QVVEDHRAVF QESIRWIEDE KALLEMTEEV DYDVDSYATQ 660
LEAILEQKID ILTELRDKVK SFRAALQEEE QASKQINPKR PRAL 704

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF2AG3N277Bos taurusPredictionMore>>
1:1 orthologKIF2AJ9P9X3Canis lupus familiarisPredictionMore>>
1:1 orthologKIF2A102180081A0A452EHH5Capra hircusPredictionMore>>
1:1 orthologKIF2A3796O00139Homo sapiensPublicationMore>>
1:1 orthologKif2a16563P28740Mus musculusPredictionMore>>
1:1 orthologKIF2A100615381K7C9U3Pan troglodytesPredictionMore>>
1:1 orthologKIF2AA0A287ADF2Sus scrofaPredictionMore>>
1:1 orthologKif2aF1M8L1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0120103 centriolar subdistal appendage
GO:0005814 centriole
GO:0005813 centrosome
GO:0005737 cytoplasm
GO:0016604 nuclear body
GO:0005730 nucleolus
GO:0097228 sperm principal piece
GO:0005876 spindle microtubule
GO:0000922 spindle pole
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0007018 microtubule-based movement
GO:0090307 mitotic spindle assembly
GO:0030334 regulation of cell migration

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0493 Microtubule
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin