Gene: KIF2A

Basic information

Tag Content
Uniprot ID K7C9U3; A0A2J8L1G7;
Entrez ID 100615381
Genbank protein ID JAA04978.1; JAA30726.1; JAA15642.1; JAA35951.1;
Genbank nucleotide ID XM_016953266.1
Ensembl protein ID ENSPTRP00000085238
Ensembl nucleotide ID ENSPTRG00000016913
Gene name Kinesin-like protein
Gene symbol KIF2A
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATANFGKIQ IGIYVEIKRS DGRIHQAMVT SLNEDNESVT VEWIENGDTK GKEIDLESIF 60
SLNPDLVPDE EIEPSPETPP PPASSAKVNK IVKNRRTVAS IKNDPPPRDN RVVGSARARP 120
SQFPEQSSSA QQNGSVSDIS PVQAAKKEFG PPSRRKSNCV KEVEKLQEKR EKRRLQQQEL 180
REKRAQDVDA TNPNYEIMCM IRDFRGSLDY RPLTTADPID EHRICVCVRK RPLNKKETQM 240
KDLDVITIPS KDVVMVHEPK QKVDLTRYLE NQTFRFDYAF DDSAPNEMVY RFTARPLVET 300
IFERGMATCF AYGQTGSGKT HTMGGDFSGK NQDCSKGIYA LAARDVFLML KKPNYKKLEL 360
QVYATFFEIY SGKVFDLLNR KTKLRVLEDG KQQVQVVGLQ EREVKCVEDV LKLIDIGNSC 420
RTSGQTSANA HSSRSHAVFQ IILRRKGKLH GKFSLIDLAG NERGADTSSA DRQTRLEGAE 480
INKSLLALKE CIRALGRNKP HTPFRASKLT QVLRDSFIGE NSRTCMIATI SPGMASCENT 540
LNTLRYANRV KELTVDPTAA GDVRPIMHHP PNQIDDLETQ WGVGSSPQRD DLKLLCEQNE 600
EEVSPQLFTF HEAVSQMVEM EEQVVEDHRA VFQESIRWLE DEKALLEMTE EVDYDVDSYA 660
TQLEAILEQK IDILTELRDK VKSFRAALQE EEQASKQINP KRPRAL 706

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF2AG3N277Bos taurusPredictionMore>>
1:1 orthologKIF2AJ9P9X3Canis lupus familiarisPredictionMore>>
1:1 orthologKIF2A102180081A0A452EHH5Capra hircusPredictionMore>>
1:1 orthologKIF2A3796O00139Homo sapiensPublicationMore>>
1:1 orthologKif2a16563P28740Mus musculusPredictionMore>>
1:1 orthologKIF2A100615381K7C9U3Pan troglodytesPredictionMore>>
1:1 orthologKIF2AA0A287ADF2Sus scrofaPredictionMore>>
1:1 orthologKif2aF1M8L1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005874 microtubule
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0007018 microtubule-based movement

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0493 Microtubule
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin