Gene: KIF2A

Basic information

Tag Content
Uniprot ID G3N277
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSBTAP00000055986
Ensembl nucleotide ID ENSBTAG00000015022
Gene name Kinesin-like protein
Gene symbol KIF2A
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MATANFGKIQ IGIYVEIKRS DGRIHQAMVT SLNEDNESVT VEWIENGDTK GKEIDLESIF 60
SLNPDLVPDE DIEPSPETPP PPTSSAKVNK IVKNRRTVAS IKNEPPPRDN RVVGSARARP 120
SQLPEQSSSA QQNGSVSDIS PVQAAKKEFG PPSRRKSNCV KEVEKLQEKR EKRRLQQQEL 180
REKRAQDVDA TNPNYEIMCM IRDFRGSLDY RPLTTADPID EHRICVCVRK RPLNKKETQM 240
KDLDVITIPS KDVVMVHEPK QKVDLTRYLE NQTFRFDYAF DDSAPNEMVY RFTARPLVET 300
IFERGMATCF AYGQTGSGKT HTMGGDFSGK NQDCSKGIYA LAARDVFLML KKPNYKKLEL 360
QVYATFFEIY SGKVFDLLNR KTKLRVLEDG KQQVQVVGLQ EREVKCVEDV LKLIDIGNSC 420
RTSGQTSANA HSSRSHAVFQ IILRRKGKLH GKFSLIDLAG NERGADTSSA DRQTRLEGAE 480
INKSLLALKE CIRALGRNKP HTPFRASKLT QVLRDSFIGE NSRTCMIATI SPGMASCENT 540
LNTLRYANRV KEFGISPSDI PFSQGSGSRP DLSPSYEYDD FSPSITRVKE LTVDPTAAGD 600
VRPIMHHPPN QIDDLEAQWG VGSSPQRDDL KLLCEQNEEE VSPQLFTFHE AVSQMVEMEE 660
QVVEDHRAVF QESIRWLEDE KALLEMTEEV DYDVDSYATQ LEAILEQKID ILTELRDKVK 720
SFRAALQEEE QASKQINPKR PRAL 744

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF2AG3N277Bos taurusPredictionMore>>
1:1 orthologKIF2AJ9P9X3Canis lupus familiarisPredictionMore>>
1:1 orthologKIF2A102180081A0A452EHH5Capra hircusPredictionMore>>
1:1 orthologKIF2A3796O00139Homo sapiensPublicationMore>>
1:1 orthologKif2a16563P28740Mus musculusPredictionMore>>
1:1 orthologKIF2A100615381K7C9U3Pan troglodytesPredictionMore>>
1:1 orthologKIF2AA0A287ADF2Sus scrofaPredictionMore>>
1:1 orthologKif2aF1M8L1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0120103 centriolar subdistal appendage
GO:0005814 centriole
GO:0005813 centrosome
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0016604 nuclear body
GO:0005730 nucleolus
GO:0097228 sperm principal piece
GO:0005819 spindle
GO:0005876 spindle microtubule
GO:0000922 spindle pole
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0007018 microtubule-based movement
GO:0090307 mitotic spindle assembly
GO:0030334 regulation of cell migration

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0493 Microtubule
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin