Gene: HOXB7

Basic information

Tag Content
Uniprot ID F1N1K1
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSBTAP00000007292
Ensembl nucleotide ID ENSBTAG00000005546
Gene name Homeobox protein Hox-B7
Gene symbol HOXB7
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSSLYYANAL FSKYPAASSV FATGAFPEQT SCAFASNPQR PGYGAGSGAS FAASMQGLYP 60
GGGGMAGQSA AGVYAAGYGL EPSSFNMHCA PFEQNLSGVC PGDSAKAAGA KEQRDSDLAA 120
ESNFRIYPWM RSSGTDRKRG RQTYTRYQTL ELEKEFHYNR YLTRRRRIEI AHALCLTERQ 180
IKIWFQNRRM KWKKENKTSG PGAASQDKAE MEEDEEE 217

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHOXB7F1N1K1Bos taurusPredictionMore>>
1:1 orthologHOXB7608962F6UVS6Canis lupus familiarisPredictionMore>>
1:1 orthologHOXB7102168764A0A452F107Capra hircusPredictionMore>>
1:1 orthologHOXB7100146931F7AGE2Equus caballusPredictionMore>>
1:1 orthologHOXB73217P09629Homo sapiensPredictionMore>>
1:1 orthologHoxb715415P09024CPOMus musculusPublicationMore>>
1:1 orthologHOXB7455191H2QDC3Pan troglodytesPredictionMore>>
1:1 orthologHOXB7100522513F1RWG2Sus scrofaPredictionMore>>
1:1 orthologHoxb7497985P18864Rattus norvegicusPredictionMore>>
1:1 orthologhoxb7a58044Q8AWY9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0016604 nuclear body
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0009952 anterior/posterior pattern specification
GO:0048704 embryonic skeletal system morphogenesis
GO:0030099 myeloid cell differentiation
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa

PROSITE

PROSITE ID PROSITE Term
PS00032 ANTENNAPEDIA
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain