| Tag | Content |
|---|---|
| Uniprot ID | Q8AWY9; O57362; Q4PRA1; |
| Entrez ID | 58044 |
| Genbank protein ID | AAY67920.1; CAA74868.1; CAD59112.1; |
| Genbank nucleotide ID | NM_001115091.2 |
| Ensembl protein ID | ENSDARP00000072915 |
| Ensembl nucleotide ID | ENSDARG00000056030 |
| Gene name | Homeobox protein Hox-B7a |
| Gene symbol | hoxb7a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Sequence | MSSLYYANAL FSKYQVASSA FSTGVFPEQT SCAFSCSSQR ASGYGSASTG APVSSSSSVS 60 LPSMYTNGTS LSSHTQGMYP TAYELGAVSL NMHSSLFDHP NLPMVSAGDL CKAQSSGKEE 120 QRGYHQNNEN NLRIYPWMRS TGADRKRGRQ TYSRYQTLEL EKEFHFNRYL SRRRRIEIAH 180 ALCLTERQIK IWFQNRRMKW KKENKSTDRC SPAADQIGGD EEEEDDE 227 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HOXB7 | F1N1K1 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | HOXB7 | 608962 | F6UVS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 102168764 | A0A452F107 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 100146931 | F7AGE2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 3217 | P09629 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hoxb7 | 15415 | P09024 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HOXB7 | 455191 | H2QDC3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 100522513 | F1RWG2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Hoxb7 | 497985 | P18864 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | hoxb7a | 58044 | Q8AWY9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |