| Tag | Content |
|---|---|
| Uniprot ID | P18864; Q68FU9; |
| Entrez ID | 497985 |
| Genbank protein ID | AAH79340.1; AAA41342.2; |
| Genbank nucleotide ID | NM_001017480.1 |
| Ensembl protein ID | ENSRNOP00000033609 |
| Ensembl nucleotide ID | ENSRNOG00000007611 |
| Gene name | Homeobox protein Hox-B7 |
| Gene symbol | Hoxb7 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Sequence | MSSLYYANAL FSKYPAASSV FAPGAFPEQT SCAFASNPQR PGYGAGPGAP FSASVQGLYS 60 GGGGMAGQSA AGVYEAGYGL EPSSFNMHCA PFEQNLSGVC PGDPAKAAGA KEQRDSDLAA 120 ESNFRIYPWM RSSGTERKRG RQTYTRYQTL ELEKEFHYNR YLTRRRRIEI AHALCLTERQ 180 IKIWFQNRRM KWKKENKTSG PGTTGQDKAE ADEEEEEEE 219 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HOXB7 | F1N1K1 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | HOXB7 | 608962 | F6UVS6 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 102168764 | A0A452F107 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 100146931 | F7AGE2 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 3217 | P09629 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Hoxb7 | 15415 | P09024 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HOXB7 | 455191 | H2QDC3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | HOXB7 | 100522513 | F1RWG2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Hoxb7 | 497985 | P18864 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | hoxb7a | 58044 | Q8AWY9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0016604 | nuclear body |
| GO:0005634 | nucleus |
| GO:0003677 | DNA binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0030099 | myeloid cell differentiation |
| GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |