Gene: ESRP2

Basic information

Tag Content
Uniprot ID F1PA85
Entrez ID 489745
Genbank protein ID
Genbank nucleotide ID XM_014114062.1; XM_014114063.1; XM_005620797.2; XM_014114061.1;
Ensembl protein ID ENSCAFP00000030139
Ensembl nucleotide ID ENSCAFG00000020320
Gene name Epithelial splicing regulatory protein 2
Gene symbol ESRP2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MTPPPPQPPP PGPDPASDSV ADPRPAPGPL VVLFGATAGA LGPDLGSDET DLILLVWQVV 60
EPQSRQVGTL HKSLVRAEAA ALSPQCREAS GLSADSLARA EPLDKVLQQF SQLVSGDVAL 120
LGGGPYMLCT DGQQLLRQVL HPEASRKNLV LPDTFFSFYD LRREFHVQHP RARPARELTV 180
ATMAQDLGLE TDATEDDFGV WEVKTMVAVI LHLLEGPSGQ LFSKAEVVKQ KYETGPCSKA 240
DVVDSETVVR ARGLPWQSSD QDVARFFKGL NIARGGVALC LNAQGRRNGE ALIRFVDSEQ 300
RDLALQRHKH HMGVRYIEVY KATGEEFVKI AGGTSLEVAR FLSREDQVIL RLRGLPFSAG 360
PADVLGFLGP ECPVTGGADG LLFVRHPDGR PTGDAFALFA CEELAQAALR RHKGILGKRY 420
IELFRSTAAE VQQVLNRYAS SPLLPALTAP LLPIPFPLAA GTGRDCVRLR GLPYTATIED 480
ILSFLGEAAA DIRPHGVHMV LNQQGRPSGD AFIQMTSAER ALAAAQRCHK KVMKERYVEV 540
VPCSTEEMSR VLMGGTLGRS GMSPPPCKLP CLSPPTYATF QATPTLIPAE TAALYPSSAL 600
LPAARVPAAP TPVAYYPGPA TQLYMNYTAY YPSPPVSPTT VGYLTTPPAA LASASTSVLS 660
QPGALVRMQG VPYTAGMKDL LSVFQAYQLA PDDYTSLVPV GDPPRTVLQA PKEWVCL 717

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologESRP2489745F1PA85Canis lupus familiarisPredictionMore>>
1:1 orthologESRP2102181230A0A452FYS9Capra hircusPredictionMore>>
1:1 orthologESRP280004Q9H6T0Homo sapiensPredictionMore>>
1:1 orthologEsrp277411Q8K0G8CLPMus musculusPublicationMore>>
1:1 orthologESRP2A0A2I3SHP8Pan troglodytesPredictionMore>>
1:1 orthologESRP2100355035G1SF15Oryctolagus cuniculusPredictionMore>>
1:1 orthologEsrp2307810G3V8M2Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005654 nucleoplasm
GO:0003729 mRNA binding
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0043484 regulation of RNA splicing

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR034431 ESRP2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR000504 RRM_dom

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term