Gene: Esrp2

Basic information

Tag Content
Uniprot ID G3V8M2
Entrez ID 307810
Genbank protein ID EDL92436.1
Genbank nucleotide ID NM_001107423.1
Ensembl protein ID ENSRNOP00000026873
Ensembl nucleotide ID ENSRNOG00000023177
Gene name Epithelial-splicing regulatory protein 2
Gene symbol Esrp2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MTPPPPPPPP PGPDPAVDSS TDPCPEPQSL VVLFGATAGA LGPDLGSDET DLILLVWQVV 60
EPRSRQVGTL HKSLVRAEAA ALSPQCREAS GLSADSLARA ESLDKVLQQF SQLVSGDVAL 120
LGGGPYVLCT DGQQLLRQVL HPEASRKNLV LPDTFFSFYD LRREFHVQHP STCSARDLTV 180
GTMAQDLGLE TDATEDDFGV WEVKTMVAVI LHLLEGPNGH LFSKPEVVKQ KYETGPCSKA 240
DVVDNETVVR ARGLPWQSSD QDVARFFKGL NIARGGVALC LNAQGRRNGE ALIRFEDSEQ 300
RDLALQRHKH HMGVRYIEVY KATGEEFVKI AGGTSLEVAR FLSREDQVIL RLRGLPFSAG 360
PADVLDFLGP ECPVTGGVDG LLFVRHPDGR PTGDAFALFA CEELAQAALR RHKGMLGKRY 420
IELFRSTAAE VQQVLNRYAA SPLLPTLTAP LLPIPFPLAG GTGRDCVRLR GLPYTATIED 480
ILSFLGEAAA DIRPHGVHMV LNQQGRPSGD AFIQMMSVER ALAAAQRCHK KVMKERYVEV 540
VPCSTEEMSR VLMGGSLSRS GLSPPPCKLP CLSPPTYATF QASPALIPTE TTALYPSSAL 600
LPAARVPAAA TPLAYYPGPA TQLYMNYTAY YPSPPVSPTT VGYLTTPPTA LASTPTSMLS 660
QPGALVRMQG VPYTAGMKDL LSVFQAYQLA PDDYATLVPV GDPPRTVLQA PKEWVCL 717

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologESRP2489745F1PA85Canis lupus familiarisPredictionMore>>
1:1 orthologESRP2102181230A0A452FYS9Capra hircusPredictionMore>>
1:1 orthologESRP280004Q9H6T0Homo sapiensPredictionMore>>
1:1 orthologEsrp277411Q8K0G8CLPMus musculusPublicationMore>>
1:1 orthologESRP2A0A2I3SHP8Pan troglodytesPredictionMore>>
1:1 orthologESRP2100355035G1SF15Oryctolagus cuniculusPredictionMore>>
1:1 orthologEsrp2307810G3V8M2Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005654 nucleoplasm
GO:0003729 mRNA binding
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0060445 branching involved in salivary gland morphogenesis
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0043484 regulation of RNA splicing

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR034431 ESRP2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
IPR000504 RRM_dom

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term