| Tag | Content |
|---|---|
| Uniprot ID | F1PQ93 |
| Entrez ID | 487351 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005617741.1 |
| Ensembl protein ID | ENSCAFP00000018103 |
| Ensembl nucleotide ID | ENSCAFG00000012290 |
| Gene name | Stratifin |
| Gene symbol | SFN |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MERASLIQKA KLAEQAERYE DMAAFMKSAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR 60 VLSSIEQKGN EESSEEKGPE VREYREKVET ELRGVCDTVL GLLDSHLIKE AGDAESRVFY 120 LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH 180 YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG 240 EAPEEPQS 248 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SFN | 528453 | Q0VC36 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SFN | 487351 | F1PQ93 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SFN | 102190744 | A0A452DME8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SFN | 100057082 | F7CIM1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SFN | 2810 | P31947 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sfn | 55948 | O70456 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SFN | 737412 | H2RC87 | Pan troglodytes | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0042802 | identical protein binding |
| GO:0051219 | phosphoprotein binding |
| GO:0019901 | protein kinase binding |
| GO:0061436 | establishment of skin barrier |
| GO:0008630 | intrinsic apoptotic signaling pathway in response to DNA damage |
| GO:0031424 | keratinization |
| GO:0003334 | keratinocyte development |
| GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| GO:0010839 | negative regulation of keratinocyte proliferation |
| GO:0030307 | positive regulation of cell growth |
| GO:0045606 | positive regulation of epidermal cell differentiation |
| GO:0046827 | positive regulation of protein export from nucleus |
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity |
| GO:0010482 | regulation of epidermal cell division |
| GO:0001836 | release of cytochrome c from mitochondria |
| Pfam ID | Pfam Term |
|---|---|
| PF00244 | 14-3-3 |