Gene: rspo2

Basic information

Tag Content
Uniprot ID F1Q5C9
Entrez ID 566054
Genbank protein ID BAN10331.1
Genbank nucleotide ID NM_001281990.1
Ensembl protein ID ENSDARP00000147947; ENSDARP00000100941;
Ensembl nucleotide ID ENSDARG00000079570; ENSDARG00000113124;
Gene name R-spondin 2
Gene symbol rspo2
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MQFRLFSFAL IVLNCVDYSH CQTQQSHRWR RNKRASYGAY PICKGCSVCS KDNGCMNCQP 60
KLFLFLRRER MRQYGECLHA CPSGYYGMRG TEINMCSRCR IDDCEACFSK DFCTKCKLGF 120
YLHKGRCFEK CPEGFAPLED TMECGEGCEV GQWSEWGTCA RRNKTCGFKW GLETRTRHIV 180
KKPPKDTIPC PTIAESRRCK MAMRHCRKGG SGKGHRTKDQ KKKSNKQRLR LRAQNQHSDH 240
LASIRAGQ 248

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRSPO2482004F1P932Canis lupus familiarisPredictionMore>>
1:1 orthologRSPO2100860771A0A452FDY5Capra hircusPredictionMore>>
1:1 orthologRSPO2100056523A8C9U1Equus caballusPredictionMore>>
1:1 orthologRSPO2340419Q6UXX9Homo sapiensPredictionMore>>
1:1 orthologRspo2239405Q8BFU0CPO,CLPE14.5, E15.5Mus musculusPublicationMore>>
1:1 orthologRSPO2464335A0A2I3RH49Pan troglodytesPredictionMore>>
1:1 orthologRSPO2A0A5G2RDB4Sus scrofaPredictionMore>>
1:1 orthologRspo2500863I7GAZ6Rattus norvegicusPredictionMore>>
1:1 orthologrspo2566054F1Q5C9Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0008201 heparin binding
GO:0033335 anal fin development
GO:0033336 caudal fin development
GO:0033337 dorsal fin development
GO:0033338 medial fin development
GO:0033339 pectoral fin development
GO:0033340 pelvic fin development
GO:0030177 positive regulation of Wnt signaling pathway
GO:0001501 skeletal system development
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0358 Heparin-binding
KW-1185 Reference proteome
KW-0716 Sensory transduction
KW-0732 Signal
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR006212 Furin_repeat
IPR009030 Growth_fac_rcpt_cys_sf
IPR042993 RSPO2/4
IPR043601 Rspo_Fu-CRD_dom
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf

PROSITE

PROSITE ID PROSITE Term
PS50092 TSP1

Pfam

Pfam ID Pfam Term
PF15913 Furin-like_2