| Tag | Content |
|---|---|
| Uniprot ID | I7GAZ6 |
| Entrez ID | 500863 |
| Genbank protein ID | BAF03041.1 |
| Genbank nucleotide ID | XM_008765454.2 |
| Ensembl protein ID | ENSRNOP00000069239 |
| Ensembl nucleotide ID | ENSRNOG00000037687 |
| Gene name | R-spondin 2 |
| Gene symbol | Rspo2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRFCLFSFAL IILNCMDYSQ CQGNRWRRSK RGGSRSPEAS YVSNPICKGC LSCSKDNGCS 60 RCQQKLFFFL RREGMRQYGE CLHSCPSGYY GHRAPDMNRC ARCRIENCDS CFSKDFCTKC 120 KAGFYLHRGR CFDECPEGFA PLDETMECVE GCEVGHWSEW GTCSRNNRTC GFKWGLETRT 180 RQIVKKPAKD TIPCPTIAES RRCKMAMRHC PGGKRTPKAK EKRNKKKRRK LIERAQEQHS 240 VFLATDRVNQ |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RSPO2 | 482004 | F1P932 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RSPO2 | 100860771 | A0A452FDY5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RSPO2 | 100056523 | A8C9U1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | RSPO2 | 340419 | Q6UXX9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Rspo2 | 239405 | Q8BFU0 | CPO,CLP | E14.5, E15.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | RSPO2 | 464335 | A0A2I3RH49 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | RSPO2 | A0A5G2RDB4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Rspo2 | 500863 | I7GAZ6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | rspo2 | 566054 | F1Q5C9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0005576 | extracellular region |
| GO:0008201 | heparin binding |
| GO:0005102 | signaling receptor binding |
| GO:0030282 | bone mineralization |
| GO:0071542 | dopaminergic neuron differentiation |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0060441 | epithelial tube branching involved in lung morphogenesis |
| GO:0060173 | limb development |
| GO:0060437 | lung growth |
| GO:0042489 | negative regulation of odontogenesis of dentin-containing tooth |
| GO:0001649 | osteoblast differentiation |
| GO:0090263 | positive regulation of canonical Wnt signaling pathway |
| GO:0030177 | positive regulation of Wnt signaling pathway |
| GO:0060535 | trachea cartilage morphogenesis |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50092 | TSP1 |
| Pfam ID | Pfam Term |
|---|---|
| PF15913 | Furin-like_2 |