| Tag | Content |
|---|---|
| Uniprot ID | F1QBI2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000071107 |
| Ensembl nucleotide ID | ENSDARG00000054438 |
| Gene name | Frizzled class receptor 2 |
| Gene symbol | fzd2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQASGSVCVF LALLLPCCFV ASGQHQGDNG IAVPDHGFCQ PITIPLCTDI AYNQTIMPNL 60 VGHYNQDDAG LEVHQFYPLV KVQCSPELKF FLCSMYAPVC TVLEKAIPPC RSICERAKQG 120 CEVLMNKFGF QWPEALRCEH FPVLGDGHIC VGQNDSMATV SPVHMPIPGT PSVQLYSTPD 180 KPFRCPSTLK VPAYLSYKFL GEPDCGAPCE SSRTHRAYMF FTDQEIEFAR IWILIWSSLC 240 CASTLFTVTT YIVDMQRFKY PERPIIFLSG CYTMVSIAYI AGYFLGDKVV CNESFFPDSY 300 KTIVQGTKKE GCTILFMMLY FFSMASSIWW VILSLTWFLA AGMKWGHEAI EANSQYFHLA 360 AWAVPAVKTI SILAMGQIDG DVLSGVCFVG LNNSDALRGF ILAPLFLYLF IGTSFLLAGF 420 VSLFRIRTIM KHDGTKTEKL ERLMVRIGVF SVLYTVPATI VIACFFYEQA FRQQWEKSWI 480 SMNCKSLAIP CPMQPAPHMT PDFTVFMIKY LMTLIVGITS GFWIWSGKTL HSWQKFYVRL 540 TSAGQGETTV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD2 | 2535 | Q14332 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fzd2 | 57265 | Q9JIP6 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FZD2 | H2QD74 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Fzd2 | G3V954 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | fzd2 | F1QBI2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0016477 | cell migration |
| GO:0060271 | cilium assembly |
| GO:0060027 | convergent extension involved in gastrulation |
| GO:0007368 | determination of left/right symmetry |
| GO:0031018 | endocrine pancreas development |
| GO:0003146 | heart jogging |
| GO:0001947 | heart looping |
| GO:0061341 | non-canonical Wnt signaling pathway involved in heart development |
| GO:0070654 | sensory epithelium regeneration |
| GO:0007223 | Wnt signaling pathway, calcium modulating pathway |