| Tag | Content |
|---|---|
| Uniprot ID | H2QD74 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000015783 |
| Ensembl nucleotide ID | ENSPTRG00000009279 |
| Gene name | Frizzled class receptor 2 |
| Gene symbol | FZD2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | QFLQILGFHG EKGISIPDHG FCQPISIPLC TDIAYNQTIM PNLLGHTNQE DAGLEVHQFY 60 PLVKVQCSPE LRFFLCSMYA PVCTVLEQAI PPCRSICERA RQGCEALMNK FGFQWPERLR 120 CEHFPRHGAE QICVGQNHSE DGAPALLTTA PPPGLQPGAG GTPGGPGGGG APPRYATLEH 180 PFHCPRVLKV PSYLSYKFLG ERDCAAPCEP ARPDGSMFFS QEETRFARLW ILTWSVLCCA 240 STFFTVTTYL VDMQRFRYPE RPIIFLSGCY TMVSVAYIAG FVLQERVVCN ERFSEDGYRT 300 VVQGTKKEGC TILFMMLYFF SMASSIWWVI LSLTWFLAAG MKWGHEAIEA NSQYFHLAAW 360 AVPAVKTITI LAMGQIDGDL LSGVCFVGLN SLDPLRGFVL APLFVYLFIG TSFLLAGFVS 420 LFRIRTIMKH DGTKTEKLER LMVRIGVFSV LYTVPATIVI ACYFYEQAFR EHWERSWVSQ 480 HCKSLAIPCP AHYTPRMSPD FTVYMIKYLM TLIVGITSGF WIWSGKTLHS WRKFYTRLTN 540 SRHGETTV 548 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FZD2 | 2535 | Q14332 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Fzd2 | 57265 | Q9JIP6 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FZD2 | H2QD74 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Fzd2 | G3V954 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | fzd2 | F1QBI2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0030165 | PDZ domain binding |
| GO:0042813 | Wnt-activated receptor activity |
| GO:0017147 | Wnt-protein binding |
| GO:0060070 | canonical Wnt signaling pathway |
| GO:0090103 | cochlea morphogenesis |
| GO:0030855 | epithelial cell differentiation |
| GO:0060022 | hard palate development |
| GO:0060119 | inner ear receptor cell development |
| GO:0003149 | membranous septum morphogenesis |
| GO:0003150 | muscular septum morphogenesis |
| GO:0003151 | outflow tract morphogenesis |
| GO:0090179 | planar cell polarity pathway involved in neural tube closure |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity |
| GO:0045745 | positive regulation of G protein-coupled receptor signaling pathway |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:0007608 | sensory perception of smell |