Gene: YOD1

Basic information

Tag Content
Uniprot ID F1RTR7
Entrez ID 100520400
Genbank protein ID HDA49145.1
Genbank nucleotide ID XM_005667548.2; XM_005667547.2;
Ensembl protein ID ENSSSCP00000016602
Ensembl nucleotide ID ENSSSCG00000015659
Gene name Ubiquitin thioesterase OTU1 isoform 2
Gene symbol YOD1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MQSLHITYSD LEAFTVEGLS SRTRVRELQG QIAAITGIAP DCQRILVGYP PECLDLSEGD 60
TILGDLPIQS GDMLIVEEDQ TRPKTSPAFT KHGAPSYVRE PLPVLTRTTV PADNSCLFTS 120
VYYVVEGGVL NPACAPEMRR LIAQIVASDP DFYSEAILGK TNQEYCDWIK RDDTWGGAIE 180
ISILSKFYQC EICVVDTQTV RIDRFGEDAG YTKRVLLIYD GIHYDPLQRV FPDPDTPPLT 240
IFSSNDDIVL VQALELADEA RSKRQFTDVN RFTLRCMVCQ KGLTGQAEAR DHAKETGHTN 300
FGEV 304

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologYOD1539931Q05B57Bos taurusPredictionMore>>
1:1 orthologYOD1490268E2R1N1Canis lupus familiarisPredictionMore>>
1:1 orthologYOD1102177549A0A452EJV7Capra hircusPredictionMore>>
1:1 orthologYOD155432Q5VVQ6Homo sapiensPublicationMore>>
1:1 orthologYod1226418Q8CB27Mus musculusPredictionMore>>
1:1 orthologYOD1469659G2HE61Pan troglodytesPredictionMore>>
1:1 orthologYOD1100520400F1RTR7Sus scrofaPredictionMore>>
1:1 orthologYOD1U3KMW5Oryctolagus cuniculusPredictionMore>>
1:1 orthologYod1363982Q32Q05Rattus norvegicusPredictionMore>>
1:1 orthologyod1550411Q567B1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:1990380 Lys48-specific deubiquitinase activity
GO:0003676 nucleic acid binding
GO:0004843 thiol-dependent ubiquitin-specific protease activity
GO:0031625 ubiquitin protein ligase binding
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0016236 macroautophagy
GO:1904153 negative regulation of retrograde protein transport, ER to cytosol
GO:0035871 protein K11-linked deubiquitination
GO:1990167 protein K27-linked deubiquitination
GO:0035523 protein K29-linked deubiquitination
GO:1990168 protein K33-linked deubiquitination
GO:0070536 protein K63-linked deubiquitination
GO:0030433 ubiquitin-dependent ERAD pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR039138 OTU1_2_3
IPR003323 OTU_dom
IPR038765 Papain-like_cys_pep_sf
IPR029071 Ubiquitin-like_domsf
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS50802 OTU
PS00028 ZINC_FINGER_C2H2_1

Pfam

Pfam ID Pfam Term
PF02338 OTU