Gene: TGFB2

Basic information

Tag Content
Uniprot ID F1S9L0
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000011530
Ensembl nucleotide ID ENSSSCG00000010816
Gene name Transforming growth factor beta
Gene symbol TGFB2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHYCVLSAFL LLHLVTVALS LSTCSTLDMD QFMRKRIEAI RGQILSKLKL TSPPEDYPEP 60
EEVPPEVISI YNSTRDLLQE KASRRAAACE RERSDEEYYA KEVYKIDMPP FFPSENAIPP 120
TFYRPYFRIV RFDVSAMEKN ASNLVKAEFR VFRLQNPKAR VAEQRIELYQ ILKSKDLTSP 180
TQRYIDSKVV KTRAEGEWLS FDVTDAVHEW LHHKDRNLGF KISLHCPCCT FVPSNNYIIP 240
NKSEELEARF AGIDGTSTYT SGDQKTIKST RKKNSGKTPH LLLMLLPSYR LESQQSNRRK 300
KRALDAAYCF RNVQDNCCLR PLYIDFKRDL GWKWIHEPKG YNANFCAGAC PYLWSSDTQH 360
SRVLSLYNTI NPEASASPCC VSQDLEPLTI LYYIGKTPKI EQLSNMIVKS CKCRKSKLAS 420
AAGLDHSHSN SGSEL 435

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTGFB2534069P21214Bos taurusPredictionMore>>
1:1 orthologTGFB2488596F1PKH2Canis lupus familiarisPredictionMore>>
1:1 orthologTGFB2100861228A0A452FPN4Capra hircusPredictionMore>>
1:1 orthologTGFB2100050377F6WJJ3Equus caballusPredictionMore>>
1:1 orthologTGFB27042P61812Homo sapiensPublicationMore>>
1:1 orthologTgfb221808P27090CPOE12.5, E14.0, E13.5, E14.5, E15.5Mus musculusPublicationMore>>
1:1 orthologTGFB2A0A2I3S6G8Pan troglodytesPredictionMore>>
1:1 orthologTGFB2F1S9L0Sus scrofaPredictionMore>>
1:1 orthologTGFB2G1SNK8Oryctolagus cuniculusPredictionMore>>
1:1 orthologTgfb2G3V6B1Rattus norvegicusPredictionMore>>
1:1 orthologtgfb2F8W4A6Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0008083 growth factor activity
GO:0005160 transforming growth factor beta receptor binding
GO:0051781 positive regulation of cell division

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0339 Growth factor
KW-0497 Mitogen
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR029034 Cystine-knot_cytokine
IPR001839 TGF-b_C
IPR001111 TGF-b_propeptide
IPR016319 TGF-beta
IPR015615 TGF-beta-rel
IPR003940 TGFb2
IPR017948 TGFb_CS

PROSITE

PROSITE ID PROSITE Term
PS00250 TGF_BETA_1
PS51362 TGF_BETA_2

Pfam

Pfam ID Pfam Term
PF00019 TGF_beta
PF00688 TGFb_propeptide