| Tag | Content |
|---|---|
| Uniprot ID | F6TQP5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_014729740.1 |
| Ensembl protein ID | ENSECAP00000020771 |
| Ensembl nucleotide ID | ENSECAG00000023341 |
| Gene name | 7-dehydrocholesterol reductase |
| Gene symbol | DHCR7 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAAKSQPNVP RTKSPDGVAK DGAAPHGQWG RAWEVDWFSL ASILFLLLFA PFIVYYFIMA 60 CDQYSCSLTA PVVDIATGRA RVSDIWAKTP SVTKKAARLY TLWVTFQVLL YMVLPDFCHK 120 FLPGYVGGVQ EGAVTPAGVV NKYQVNGLQA WVITHLLWFA NSHLFFWFSP TIIFDNWIPL 180 LWCANILGYA VSTFAMVKGY FFPTNAEDCK FTGNFFYNYM MGIEFNPRIG KWFDFKLFFN 240 GRPGIVAWTL INLSFAAKQQ ELYGHVTNSM VLVNVLQAIY VLDFFWNETW YLKTIDICHD 300 HFGWYLGWGD CVWLPYLYTL QGLYLVYHPV QLSTPHAMGV LLLGLLGYYV FRMANHQKDL 360 FRRTGGRCRI WGRKPEAIEC SYTSADGQKH RSKLLVSGFW GLARHFNYTG DLMGSLAYCL 420 ACGGGHLLPY FYIVYMTILL THRCLRDEHR CALKYGRDWE RYTTAVPYRL LPGIF 475 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DHCR7 | 483675 | E2RNQ5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | DHCR7 | A0A452EN40 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DHCR7 | F6TQP5 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | DHCR7 | 1717 | Q9UBM7 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dhcr7 | 13360 | O88455 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | DHCR7 | 451393 | H2R2E7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DHCR7 | I3LKI5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Dhcr7 | 64191 | Q9Z2Z8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dhcr7 | F1QKG5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:0005640 | nuclear outer membrane |
| GO:0047598 | 7-dehydrocholesterol reductase activity |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0009918 | sterol delta7 reductase activity |
| GO:0001568 | blood vessel development |
| GO:0016132 | brassinosteroid biosynthetic process |
| GO:0030154 | cell differentiation |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0030324 | lung development |
| GO:0035264 | multicellular organism growth |
| GO:0009791 | post-embryonic development |
| GO:0042127 | regulation of cell population proliferation |
| GO:0016126 | sterol biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF01222 | ERG4_ERG24 |