| Tag | Content |
|---|---|
| Uniprot ID | I3LKI5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000024599 |
| Ensembl nucleotide ID | ENSSSCG00000021181 |
| Gene name | 7-dehydrocholesterol reductase |
| Gene symbol | DHCR7 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAAKSQPGTP KTKSLGSVSN GSAATQGQWG RAWEVDWFSL ASVIFLLLCA PFIVYYFIMA 60 CDQYGCSLTA PLGDIATGRA RLSDIWAKTP PVTRTAAQLY TAWVTFQVLL YMLLPDFCHK 120 FLPGYVGGVQ EGAVTPAGVV NKYQINGLQA WLITHLLWFA NSHVLSWFSP TIIFDNWIPL 180 LWCANILGYA VSTFAMIKGY CFPTDARDCK FTGNFFYNYM MGIEFNPRIG KWFDFKLFFN 240 GRPGIVAWTL INLSFAAKQQ QLYGHVTNSM VLVNVLQAIY VLDFFWNETW YLKTIDICHD 300 HFGWYLGWGD CVWLPYLYTL QGLYLVYHPV QLSTPYAVGV LLLGLLGYYI FRMANHQKDL 360 FRRTDGRCLI WGRKPQVIEC SYTSADGQKH HSKLLVSGFW GVARHFNYTG DLLGSLAYCL 420 ACGGGHLLPY FYIIYMGILL THRCLRDEHR CANKYGRDWE RYTATVPYRL LPGVF 475 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DHCR7 | 483675 | E2RNQ5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | DHCR7 | A0A452EN40 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DHCR7 | F6TQP5 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | DHCR7 | 1717 | Q9UBM7 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Dhcr7 | 13360 | O88455 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | DHCR7 | 451393 | H2R2E7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DHCR7 | I3LKI5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Dhcr7 | 64191 | Q9Z2Z8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dhcr7 | F1QKG5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0030176 | integral component of endoplasmic reticulum membrane |
| GO:0005640 | nuclear outer membrane |
| GO:0047598 | 7-dehydrocholesterol reductase activity |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0009918 | sterol delta7 reductase activity |
| GO:0001568 | blood vessel development |
| GO:0016132 | brassinosteroid biosynthetic process |
| GO:0030154 | cell differentiation |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0030324 | lung development |
| GO:0035264 | multicellular organism growth |
| GO:0009791 | post-embryonic development |
| GO:0042127 | regulation of cell population proliferation |
| GO:0016126 | sterol biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF01222 | ERG4_ERG24 |