| Tag | Content |
|---|---|
| Uniprot ID | G1T5V9 |
| Entrez ID | 100009005 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001195671.1 |
| Ensembl protein ID | ENSOCUP00000011756 |
| Ensembl nucleotide ID | ENSOCUG00000013629 |
| Gene name | Uncharacterized protein |
| Gene symbol | COL2A1 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MIRLGAPQTL VLLTLLVAAA LRCQGQDVQE AGSCVQEGKR YNDKDVWKPE PCRICVCDTG 60 TVLCDDIICE DTKDCLSPEI PFGECCPVCP TDLATASGKP GPKGQKGEPG DIKDIVGPKG 120 PPGPQGPAGE QGPRGDRGDK GEKGAPGPRG RDGEPGTPGN PGPPGPPGPP GPPGLGGNFA 180 AQMAGGFDEK AGGAQMGVMQ GPMGPMGPRG PPGPAGAPGP QGFQGNPGEP GEPGVSGPMG 240 PRGPPGPPGK PGDDGEAGKP GKPGERGLPG PQGARGFPGT PGLPGVKGHR GYPGLDGAKG 300 EAGAPGVKGE SGSPGENGSP GPMGPRGLPG ERGRTGPAGA AGARGNDGQP GPAGPPGPVG 360 PAGGPGFPGA PGAKGEAGPT GARGPEGAQG PRGEPGTPGS PGPAGASGNP GTDGIPGAKG 420 SAGAPGIAGA PGFPGPRGPP GPQGATGPLG PKGQTGEPGI AGFKGEQGPK GEPDPAGPQG 480 APGPAGEEGK RGARGEPGGA GPAGPPGERG APGNRGFPGQ DGLAGPKGAP GERGPSGLAG 540 PKGANGDPGR PGEPGLPGAR GLTGRPGDAG PQGKVGPSGA PGEDGRPGPP GPQGARGQPG 600 VMGFPGPKGA NGEPGKAGEK GLPGAPGLRG LPGKDGETGA AGPPGPAGPA GERGEQGAPG 660 PSGFQGLPGP PGPPGEGGKP GDQGVPGEAG APGLVGPRGE RGFPGERGSP GAQGLQGARG 720 LPGTPGTDGP KGAPGPAGPP GAQGPPGLQG MPGERGAAGI AGPKGDRGDV GEKGPEGAPG 780 KDGGRGLTGP IGPPGPAGAN GEKGEVGPPG PAGSAGARGA PGERGETGPP GPAGFAGPPG 840 ADGQPGAKGE QGEAGQKGDA GAPGPQGPSG APGPQGPTGV TGPKGARGAQ GPPGATGFPG 900 AAGRVGPPGS NGNPGPPGPP GPSGKEGPKG ARGDSGPAGR AGDPGLQGPA GPPGLKGEPG 960 DSGPSGADGP PGPQGLAGQR GIVGLPGQRG ERGFPGLPGP SGEPGKQGAP GASGDRGPPG 1020 PVGPPGLTGP AGEPGREGSP GADGPPGRDG AAGVKGDRGE TGAVGAPGAP GPPGSPGPAG 1080 PTGKQGDRGE AGAQGPMGPS GPAGARGIPG PQGPRGDKGE SGEPGERGLK GHRGFTGLQG 1140 LPGPPGPSGD QGAAGPAGPS GPRGPPGPVG PSGKDGANGI PGPIGPPGPR GRSGETGPAG 1200 PPGNPGPPGP PGPPGPGIDM SAFAGLGQRE KGPDPLQYMR ADEAAGALRQ HDADVDATLK 1260 SLNNQIESIR SPEGSRKNPA RTCRDLQLCH PEWKSGDYWI DPNQGCTLDA MKVFCNMETG 1320 ETCVYPNPAT VPKKNWWSSK SQKQQHVWFG ETINGGFHFS YGDSSLPPNT ANVQMTFLRL 1380 LSTEGSQNIT YHCKNSVAYL DEATGNLKKA LLLQGSNDVE IRAEGNSRFT YTVLQDGCTK 1440 HTGKWGKTVI EYRSQKTSRL PITDIAPMDI GGPEQEFGVD IGPVCFL 1487 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL2A1 | 407142 | P02459 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | COL2A1 | A0A452E0F9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL2A1 | 791241 | A0A5F5PIB7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | COL2A1 | 1280 | P02458 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Col2a1 | 12824 | P28481 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | COL2A1 | 451860 | H2Q5S8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL2A1 | 100009005 | G1T5V9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Col2a1 | F1LRM7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005604 | basement membrane |
| GO:0005585 | collagen type II trimer |
| GO:0005737 | cytoplasm |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0042802 | identical protein binding |
| GO:0042289 | MHC class II protein binding |
| GO:0048407 | platelet-derived growth factor binding |
| GO:0043394 | proteoglycan binding |
| GO:0097065 | anterior head development |
| GO:0001502 | cartilage condensation |
| GO:0060351 | cartilage development involved in endochondral bone morphogenesis |
| GO:0071773 | cellular response to BMP stimulus |
| GO:0007417 | central nervous system development |
| GO:0002062 | chondrocyte differentiation |
| GO:0030199 | collagen fibril organization |
| GO:0060272 | embryonic skeletal joint morphogenesis |
| GO:0001958 | endochondral ossification |
| GO:0003007 | heart morphogenesis |
| GO:0042472 | inner ear morphogenesis |
| GO:0060174 | limb bud formation |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0030903 | notochord development |
| GO:0071599 | otic vesicle development |
| GO:0006029 | proteoglycan metabolic process |
| GO:0010468 | regulation of gene expression |
| GO:0060021 | roof of mouth development |
| GO:0007605 | sensory perception of sound |
| GO:0001894 | tissue homeostasis |
| GO:0007601 | visual perception |