Gene: SERPINH1

Basic information

Tag Content
Uniprot ID G2HFZ7; A0A2J8MB94;
Entrez ID 466899
Genbank protein ID JAA40893.1; JAA40891.1; BAK62655.1;
Genbank nucleotide ID XM_009423647.2; NM_001246610.1;
Ensembl protein ID ENSPTRP00000007020
Ensembl nucleotide ID ENSPTRG00000004083
Gene name Collagen-binding protein 2
Gene symbol SERPINH1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRSLLLLSAF CLLEAALAAE VKKPAAAAAP GTAEKLSPKA ATLAERSAGL AFSLYQAMAK 60
DQAVENILVS PVVVASSLGL VSLGGKATTA SQAKAVLSAE QLRDEEVHAG LGELLRSLSN 120
STARNVTWKL GSRLYGPSSV SFADDFVRSS KQHYNCEHSK INFRDKRSAL QSINEWAAQT 180
TDGKLPEVTK DVERTDGALL VNAMFFKPHW DEKFHHKMVD NRGFMVTRSY TVGVMMMHRT 240
GLYNYYDDEK EKLQIVEMPL AHKLSSLIIL MPHHVEPLER LEKLLTKEQL KIWMGKMQKK 300
AVAISLPKGV VEVTHDLQKH LAGLGLTEAI DKNKADLSRM SGKKDLYLAS VFHATAFELD 360
TDGNPFDQDI YGREELRSPK LFYADHPFIF LVRDTQSGSL LFIGRLVRPK GDKMRDEL 418

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSERPINH1510850Q2KJH6Bos taurusPredictionMore>>
1:1 orthologSERPINH1485187E2RHY7Canis lupus familiarisPredictionMore>>
1:1 orthologSERPINH1102171265A0A452DNR6Capra hircusPredictionMore>>
1:1 orthologSERPINH1F6PWV8Equus caballusPredictionMore>>
1:1 orthologSERPINH1871P50454Homo sapiensPredictionMore>>
1:1 orthologSerpinh112406P19324CPOMus musculusPublicationMore>>
1:1 orthologSERPINH1466899G2HFZ7Pan troglodytesPredictionMore>>
1:1 orthologSERPINH1A0A286ZRU9Sus scrofaPredictionMore>>
1:1 orthologSerpinh1Q5RJR9Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005581 collagen trimer
GO:0005783 endoplasmic reticulum
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005615 extracellular space
GO:0045121 membrane raft
GO:0005518 collagen binding
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0051082 unfolded protein binding
GO:0003433 chondrocyte development involved in endochondral bone morphogenesis
GO:0032964 collagen biosynthetic process
GO:0030199 collagen fibril organization
GO:0010951 negative regulation of endopeptidase activity
GO:0051604 protein maturation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0176 Collagen
KW-1185 Reference proteome
KW-0732 Signal
KW-0346 Stress response

Interpro

InterPro ID InterPro Term
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR033830 Serpin_H1_domain
IPR036186 Serpin_sf
IPR042178 Serpin_sf_1
IPR042185 Serpin_sf_2
IPR033547 SERPINH1

PROSITE

PROSITE ID PROSITE Term
PS00284 SERPIN

Pfam

Pfam ID Pfam Term
PF00079 Serpin