| Tag | Content |
|---|---|
| Uniprot ID | Q5RJR9 |
| Entrez ID | |
| Genbank protein ID | AAH86529.1; EDM18411.1; EDM18413.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000022983; ENSRNOP00000070279; |
| Ensembl nucleotide ID | ENSRNOG00000016831 |
| Gene name | Serine (Or cysteine) proteinase inhibitor, clade H, member 1, isoform CRA_b |
| Gene symbol | Serpinh1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRSLLLGTLC LLAVALAAEV KKPVEATAPG TAEKLSSKAT TLAERSTGLA FSLYQAMAKD 60 QAVENILLSP LVVASSLGLV SLGGKATTAS QAKAVLSAEK LRDEEVHTGL GELLRSLSNS 120 TARNVTWKLG SRLYGPSSVS FADDFVRSSK QHYNCEHSKI NFRDKRSALQ SINEWASQTT 180 DGKLPEVTKD VERTDGALLV NAMFFKPHWD EKFHHKMVDN RGFMVTRSYT VGVTMMHRTG 240 LYNYYDDEKE KLQLVEMPLA HKLSSLIILM PHHVEPLERL EKLLTKEQLK TWMGKMQKKA 300 VAISLPKGVV EVTHDLQKHL AGLGLTEAID KNKADLSRMS GKKDLYLASV FHATAFEWDT 360 EGNPFDQDIY GREELRSPKL FYADHPFIFL VRDNQSGSLL FIGRLVRPKG DKMRDEL 417 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SERPINH1 | 510850 | Q2KJH6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SERPINH1 | 485187 | E2RHY7 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SERPINH1 | 102171265 | A0A452DNR6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SERPINH1 | F6PWV8 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | SERPINH1 | 871 | P50454 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Serpinh1 | 12406 | P19324 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SERPINH1 | 466899 | G2HFZ7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SERPINH1 | A0A286ZRU9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Serpinh1 | Q5RJR9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005783 | endoplasmic reticulum |
| GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment |
| GO:0005615 | extracellular space |
| GO:0045121 | membrane raft |
| GO:0005518 | collagen binding |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0051082 | unfolded protein binding |
| GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis |
| GO:0032964 | collagen biosynthetic process |
| GO:0030199 | collagen fibril organization |
| GO:0051604 | protein maturation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00284 | SERPIN |
| Pfam ID | Pfam Term |
|---|---|
| PF00079 | Serpin |