| Tag | Content |
|---|---|
| Uniprot ID | G3V8M6 |
| Entrez ID | 171049 |
| Genbank protein ID | EDM18257.1; EDM18258.1; EDM18259.1; EDM18255.1; EDM18256.1; |
| Genbank nucleotide ID | XM_017588712.1; XM_017588713.1; NM_133527.2; XM_017588710.1; XM_006229842.3; XM_017588711.1; |
| Ensembl protein ID | ENSRNOP00000026962; ENSRNOP00000071311; |
| Ensembl nucleotide ID | ENSRNOG00000019902 |
| Gene name | Folate receptor 1 (Adult), isoform CRA_b |
| Gene symbol | Folr1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAHLMAGQWL LLLMWMAECA QSRATRARTE LLNVCMDAKH HKEKPGPEDK LHDQCSPWKT 60 NACCSTNTSQ EAHKDISYLY RFNWNHCGTM TPECKRHFIQ DTCLYECSPN LGPWIQQVDQ 120 SWRKERILDV PLCKEDCVLW WEDCKSSFTC KSNWHKGWNW TSGHNECPVG ASCHPFTFYF 180 PTPAVLCEKI WSHSYKLSNY SRGSGRCIQM WFDPAQGNPN EEVARFYAEV MSGAGLREAW 240 LLVCSLSLVL FWVLS 255 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOLR1 | 2348 | P15328 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Folr1 | 14275 | P35846 | CPO,CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | FOLR1 | 451401 | A0A2J8PZV0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOLR1 | A0A287BP62 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | FOLR2 | 100342424 | G1SCR2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Folr1 | 171049 | G3V8M6 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031362 | anchored component of external side of plasma membrane |
| GO:0046658 | anchored component of plasma membrane |
| GO:0016324 | apical plasma membrane |
| GO:0016323 | basolateral plasma membrane |
| GO:0005903 | brush border |
| GO:0031526 | brush border membrane |
| GO:0005634 | nucleus |
| GO:0008144 | drug binding |
| GO:0005542 | folic acid binding |
| GO:0061714 | folic acid receptor activity |
| GO:0051870 | methotrexate binding |
| GO:0038023 | signaling receptor activity |
| GO:0061713 | anterior neural tube closure |
| GO:0031103 | axon regeneration |
| GO:0003253 | cardiac neural crest cell migration involved in outflow tract morphogenesis |
| GO:0071231 | cellular response to folic acid |
| GO:1904447 | folate import across plasma membrane |
| GO:0046655 | folic acid metabolic process |
| GO:0015884 | folic acid transport |
| GO:0001947 | heart looping |
| GO:0003147 | neural crest cell migration involved in heart formation |
| GO:0061626 | pharyngeal arch artery morphogenesis |
| GO:0060828 | regulation of canonical Wnt signaling pathway |
| GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway |
| GO:0048678 | response to axon injury |
| Pfam ID | Pfam Term |
|---|---|
| PF03024 | Folate_rec |