| Tag | Content |
|---|---|
| Uniprot ID | H2Q4B5; A0A2J8QAG3; |
| Entrez ID | 466693 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016922441.1 |
| Ensembl protein ID | ENSPTRP00000006880 |
| Ensembl nucleotide ID | ENSPTRG00000004001 |
| Gene name | Fibroblast growth factor |
| Gene symbol | FGF3 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGLIWLLLLS LLEPGWPAAG PGARLRRDAG GRGGVYEHLG GAPRRRKLYC ATKYHLQLHP 60 SGRVNGSLEN SAYSILEITA VEVGIVAIRG LFSGRYLAMN KRGRLYASEH YSAECEFVER 120 IHELGYNTYA SRLYRTVSST PGARRQPSAE KLWYVSVNGK GRPRRGFKTR RTQKSSLFLP 180 RVLDHRDHEM VRQLQSGLPR PPGKGVQPRR RRQKQSPDNL EPSHIQASRL GSQLEASAH 239 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FGF3 | 108634211 | A0A452DMM2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FGF3 | 2248 | P11487 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Fgf3 | 14174 | Q0VG15 | E14.5, E16.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FGF3 | 466693 | H2Q4B5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Fgf3 | 170633 | Q8R5L9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | fgf3 | 30549 | P48802 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0005104 | fibroblast growth factor receptor binding |
| GO:0008083 | growth factor activity |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0055026 | negative regulation of cardiac muscle tissue development |
| GO:0008284 | positive regulation of cell population proliferation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00247 | HBGF_FGF |
| Pfam ID | Pfam Term |
|---|---|
| PF00167 | FGF |