| Tag | Content |
|---|---|
| Uniprot ID | Q8R5L9; F1LSR1; |
| Entrez ID | 170633 |
| Genbank protein ID | EDM12254.1; EDM12253.1; BAB84564.1; |
| Genbank nucleotide ID | NM_130817.1 |
| Ensembl protein ID | ENSRNOP00000028343 |
| Ensembl nucleotide ID | ENSRNOG00000020888 |
| Gene name | Fibroblast growth factor |
| Gene symbol | Fgf3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGLIWLLLLS LLEPGWPATG PGTRLRRDAG GRGGVYEHLG GAPRRRKLYC ATKYHLQLHP 60 SGRVNGSLEN SAYSILEITA VEVGVVAIKG LFSGRYLAMN KRGRLYASEH YNAECEFVER 120 IHELGYNTYA SRLYRTGPSG PGARRQPGAQ RPWYVSVNGK GRPRRGFKTR RTQKSSLFLP 180 RVLGHKDHEM VRLLQSGQPQ APGEGSQPRQ RRQKKQSPGD HGKMEHLPTK ATTSAQLDTG 240 GLAMA 245 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FGF3 | 108634211 | A0A452DMM2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FGF3 | 2248 | P11487 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Fgf3 | 14174 | Q0VG15 | E14.5, E16.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FGF3 | 466693 | H2Q4B5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Fgf3 | 170633 | Q8R5L9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | fgf3 | 30549 | P48802 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005576 | extracellular region |
| GO:0005794 | Golgi apparatus |
| GO:0005104 | fibroblast growth factor receptor binding |
| GO:0008083 | growth factor activity |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0055026 | negative regulation of cardiac muscle tissue development |
| GO:0001759 | organ induction |
| GO:0030916 | otic vesicle formation |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0036342 | post-anal tail morphogenesis |
| GO:0048752 | semicircular canal morphogenesis |
| GO:0048538 | thymus development |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00247 | HBGF_FGF |
| Pfam ID | Pfam Term |
|---|---|
| PF00167 | FGF |