| Tag | Content |
|---|---|
| Uniprot ID | P48802 |
| Entrez ID | 30549 |
| Genbank protein ID | CAA88596.1 |
| Genbank nucleotide ID | NM_131291.1 |
| Ensembl protein ID | ENSDARP00000132485 |
| Ensembl nucleotide ID | ENSDARG00000101540 |
| Gene name | Fibroblast growth factor 3 |
| Gene symbol | fgf3 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. |
| Sequence | MVIILLLLLL SFLDPSLEES LAPRLTRTPR APCARGQACD PRQRRDAGGR GGVYEHLGGA 60 PRRRKLYCAT KYHLQIHPNG KIDGSLEENN PLSILEITAV DVGVVAIKGL FSGRYLAMNE 120 KGRLYASEVF NRECEFLERI HELGYNTYAS RHHATTQPPP TGSGIGGSKR RASSKRQWYV 180 SINGKGRPRR GFKTRSTDKA SLFLPRVLAN KDHEMVRKLR ESQRHHTGSH RAPVGRAERR 240 RRRHRGSKGH NRRADI 256 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FGF3 | 108634211 | A0A452DMM2 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | FGF3 | 2248 | P11487 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Fgf3 | 14174 | Q0VG15 | E14.5, E16.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FGF3 | 466693 | H2Q4B5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Fgf3 | 170633 | Q8R5L9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | fgf3 | 30549 | P48802 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005104 | fibroblast growth factor receptor binding |
| GO:0008083 | growth factor activity |
| GO:0021984 | adenohypophysis development |
| GO:0009887 | animal organ morphogenesis |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0051216 | cartilage development |
| GO:0030154 | cell differentiation |
| GO:0001708 | cell fate specification |
| GO:0008283 | cell population proliferation |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0071696 | ectodermal placode development |
| GO:0048702 | embryonic neurocranium morphogenesis |
| GO:0009880 | embryonic pattern specification |
| GO:0060059 | embryonic retina morphogenesis in camera-type eye |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0030902 | hindbrain development |
| GO:0021854 | hypothalamus development |
| GO:0042472 | inner ear morphogenesis |
| GO:0021703 | locus ceruleus development |
| GO:0030901 | midbrain development |
| GO:0043066 | negative regulation of apoptotic process |
| GO:0014032 | neural crest cell development |
| GO:0021985 | neurohypophysis development |
| GO:0048666 | neuron development |
| GO:0048665 | neuron fate specification |
| GO:0048709 | oligodendrocyte differentiation |
| GO:0043049 | otic placode formation |
| GO:0071599 | otic vesicle development |
| GO:0030916 | otic vesicle formation |
| GO:0048840 | otolith development |
| GO:0007422 | peripheral nervous system development |
| GO:0051781 | positive regulation of cell division |
| GO:0030335 | positive regulation of cell migration |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:0010628 | positive regulation of gene expression |
| GO:0050769 | positive regulation of neurogenesis |
| GO:0045666 | positive regulation of neuron differentiation |
| GO:0001934 | positive regulation of protein phosphorylation |
| GO:0030177 | positive regulation of Wnt signaling pathway |
| GO:0048920 | posterior lateral line neuromast primordium migration |
| GO:0030334 | regulation of cell migration |
| GO:0060041 | retina development in camera-type eye |
| GO:0021571 | rhombomere 5 development |
| GO:0021572 | rhombomere 6 development |
| GO:0001501 | skeletal system development |
| GO:0060118 | vestibular receptor cell development |
| GO:0016055 | Wnt signaling pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00247 | HBGF_FGF |
| Pfam ID | Pfam Term |
|---|---|
| PF00167 | FGF |