| Tag | Content |
|---|---|
| Uniprot ID | H2Q9P8; A0A2J8NQV9; |
| Entrez ID | 453542 |
| Genbank protein ID | JAA30439.1; JAA03383.1; JAA34289.1; |
| Genbank nucleotide ID | XM_016928433.1; XM_001174876.4; |
| Ensembl protein ID | ENSPTRP00000012358 |
| Ensembl nucleotide ID | ENSPTRG00000007224 |
| Gene name | Glucuronic acid epimerase |
| Gene symbol | GLCE |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRCLAARVNY KTLIIICALF TLVTVLLWNK CSSDKAIQFP RRSSSGFRVD GFEKRAAASE 60 SNNYMNHVAK QQSEEAFPQE QQKAPPVVGG FNSNVGSKVL GLKYEEIDCL INDEHTIKGR 120 REGNEVFLPF TWVEKYFDVY GKVVQYDGYD RFEFSHSYSK VYAQRAPYHP DGVFMSFEGY 180 NVEVRDRVKC ISGVEGVPLS TQWGPQGYFY PIQIAQYGLS HYSKNLTEKP PHIEVYETAE 240 DRDKNKPNDW TVPKGCFMAN VADKSRFTNV KQFIAPETSE GVSLQLGNTK DFIISFDLKF 300 LTNGSVSVVL ETTEKNQLFT IHYVSNAQLI AFKERDIYYG IGPRTSWSTV TRDLVTDLRK 360 GVGLSNTKAV KPTKIMPKKV VRLIAKGKGF LDNITISTTA HMAAFFAASD WLVRNQDEKG 420 GWPIMVTRKL GEGFKSLEPG WYSAMAQGQA ISTLVRAYLL TKDHIFLNSA LRATAPYKFL 480 SEQHGVKAVF MNKHDWYEEY PTTPSSFVLN GFMYSLIGLY DLKETAGEKL GKEARSLYER 540 GMESLKAMLP LYDTGSGTIY DLRHFMLGIA PNLARWDYHT THINQLQLLS TIDESPIFKE 600 FVKRWKSYLK GSRAKHN 617 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLCE | 281195 | O18756 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | GLCE | 102172900 | A0A452EMT4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLCE | F7CXB5 | Equus caballus | Prediction | More>> | |||
| 1:1 ortholog | GLCE | 26035 | O94923 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Glce | 93683 | Q9EPS3 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | GLCE | 453542 | H2Q9P8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GLCE | 100154444 | F1SIU0 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Glce | 363073 | D3ZIK0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | glceb | 100007670 | F1QR43 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005794 | Golgi apparatus |
| GO:0005509 | calcium ion binding |
| GO:0047464 | heparosan-N-sulfate-glucuronate 5-epimerase activity |
| GO:0042803 | protein homodimerization activity |
| GO:0015012 | heparan sulfate proteoglycan biosynthetic process |
| GO:0030210 | heparin biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF06662 | C5-epim_C |