Gene: INSIG2

Basic information

Tag Content
Uniprot ID H2QIL8; A0A2J8M218;
Entrez ID 743385
Genbank protein ID JAA15385.1; JAA36127.1; JAA29385.1; JAA10524.1;
Genbank nucleotide ID XM_009443168.2; XM_001155360.5;
Ensembl protein ID ENSPTRP00000021225
Ensembl nucleotide ID ENSPTRG00000012395
Gene name Insulin-induced gene protein
Gene symbol INSIG2
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Mediates feedback control of cholesterol synthesis.
Sequence
MAEGETESPG PKKCGPYISS VTSQSVNLMI RGVVLFFIGV FLALVLNLLQ IQRNVTLFPP 60
DVIASIFSSA WWVPPCCGTA SAVIGLLYPC IDRHLGEPHK FKREWSSVMR CVAVFVGINH 120
ASAKVDFDNN IQLSLTLAAL SIGLWWTFDR SRSGFGLGVG IAFLATVVTQ LLVYNGVYQY 180
TSPDFLYVRS WLPCIFFAGG ITMGNIGRQL AMYECKVIAE KSHQE 225

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Gene ontology

Functional annotations

Keywords

Interpro

PROSITE

Pfam