| Tag | Content |
|---|---|
| Uniprot ID | H2R2T0; A0A2J8LKP2; |
| Entrez ID | 469353 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016920884.1 |
| Ensembl protein ID | ENSPTRP00000044424 |
| Ensembl nucleotide ID | ENSPTRG00000000868 |
| Gene name | LIM homeobox 8 |
| Gene symbol | LHX8 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSEECGRTTA LAAGRTRKGA GEEGLVSPEG AGDEDSCSSS APLSPSSSPR SMASGSGCPP 60 GKCVCNSCGL EIVDKYLLKV NDLCWHVRCL SCSVCRTSLG RHTSCYIKDK DIFCKLDYFR 120 RYGTRCSRCG RHIHSTDWVR RAKGNVYHLA CFACFSCKRQ LSTGEEFALV EEKVLCRVHY 180 DCMLDNLKRE VENGNGISVE GALLTEQDVN HPKPAKRART SFTADQLQVM QAQFAQDNNP 240 DAQTLQKLAE RTGLSRRVIQ VWFQNCRARH KKHVSPNHSS STPVTAVPPS RLSPPMLEEM 300 AYSAYVPQDG TMLTALHSYM DAHSPTTLGL QPLLPHSMTQ LPISHT 346 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LHX8 | 431707 | Q68G74 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Lhx8 | 16875 | O35652 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | LHX8 | 469353 | H2R2T0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Lhx8 | 365963 | G3V6V6 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | lhx8a | A5PMV8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0046872 | metal ion binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0006355 | regulation of transcription, DNA-templated |