Gene: AMER1

Basic information

Tag Content
Uniprot ID H2R4P7; A0A2J8L3P1;
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000047382
Ensembl nucleotide ID ENSPTRG00000028264
Gene name APC membrane recruitment protein 1
Gene symbol AMER1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
METQKDEAAQ AKGAATSGST REQTAEKGAK NKAAEATEGP TSEPSSSGPG RLKKTAMKLF 60
GGKKGICTLP SFFGGGRSKG SGKGSSKKGL SKSKTHDGLS EAAHGPEDVV SEGTGFSLPL 120
PELPCQFPSS QSAHGALETG SRCKTSVAGA TEKAVAEKVP SMPKPKKGLK GFFSSIRRHR 180
KSKVTGAEQS EPGAKGPERV RARPHEHMSS APQVPCFEET FQAPRKENAN PQDAPGPKVS 240
PTPEPSPPAT EKMACKDPEK PMEACASAHV QPKPAPEASS LEEPHSPETG EKVVAGEVNP 300
PNGPVGDPLS LLFGDVTSLK SFDSLTGCGD IIAEQDMDSM TDSMASGGQR ANRDGTKRSS 360
CLVTYQGGGE EMALPDDDDE EEEEEEEEVE LEEEEEEVKE EEEDDDLEYL WETAQMYPRP 420
NMNLGYHPTT SPGHHGHMLL DPVRSYPGLA PGELLTPQSD QQESAPNSDE GYYDSTTPGF 480
EDDSGEALGL VRRDCLPRDS YSGDALYEFY EPDDSLENSP PGDDCLYDLH GRSSEMFVPF 540
LNFEPFSSSR PPGAMETEEE RLVTIQKQLL YWELRREQLE AQEARAREAH AREAHAREAY 600
TREAYGREAY ARETHTWEAH GREARTREAQ AREVRSRETQ VRETQARQEK PVLEYQMRPL 660
GPSVMGLAAG VSGTSQISHR GITSAFPTTA SSEPDWRDFR PLEKRYEGTC SKKDQSTCLM 720
QLFQSDAMFE PDMQEANFGG SPRRAYPTYS PPEDPEEEEV EKEGNATVSF SQALVEFTSN 780
GNLFSSIRCP GTEDKRQVTQ ACGTW 805

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologAMER1100054310F6WVP3Equus caballusPredictionMore>>
1:1 orthologAMER1139285Q5JTC6Homo sapiensPredictionMore>>
1:1 orthologAmer172345Q7TS75CPOMus musculusPublicationMore>>
1:1 orthologAMER1H2R4P7Pan troglodytesPredictionMore>>
1:1 orthologAMER1100512031A0A5K1UCI1Sus scrofaPredictionMore>>
1:1 orthologAmer1501584D3ZCP6Rattus norvegicusPredictionMore>>
1:1 orthologamer1F1RDM5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005886 plasma membrane
GO:0008013 beta-catenin binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0060612 adipose tissue development
GO:0060348 bone development
GO:0072161 mesenchymal cell differentiation involved in kidney development
GO:0060828 regulation of canonical Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR019003 AMER

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF09422 WTX