| Tag | Content |
|---|---|
| Uniprot ID | J9NV13 |
| Entrez ID | 479217 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_844500.4 |
| Ensembl protein ID | ENSCAFP00000037005 |
| Ensembl nucleotide ID | ENSCAFG00000012991 |
| Gene name | AT-rich interactive domain-containing protein 5B |
| Gene symbol | ARID5B |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEPNSLQWVG SPCGLHGPYI FYKAFQFHLE GKPRILSLGD FFFVRCTPKD PICIAELQLL 60 WEERTSRQLL SSSKLYFLPE DTPQGRNSDH GEDEVIAVSE KVIVKLEDLV KWVHSDFSKW 120 RCGLQAGAVK TTALGRNGQK EALLKYRQST LNSGLNFKDV LKEKADLGED EEETNVIVLS 180 YPQYCRYRSM LKRIQDKPPS ILTDQFALAL GGIAVVSKNP QILYCRDTFD HPTLIENESI 240 CDEFAPNLKG RPRKKKPCPQ RRDSFSGVKD SNNNSDGKAV AKVKCEARSA LSKPKNNHNN 300 CKKVSNEEKP KVAIGEECRA DEQAFLVALY KYMKERKTPI ERIPYLGFKQ INLWTMFQAA 360 QKLGGYETIT ARRQWKHIYD ELGGNPGSTS AATCTRRHYE RLILPYERFI KGEEDKPLPP 420 IKPRKQENSS QENENKTKVS GTKRIKHEIP KSKKEKENAP KPQESPEVSS EPEKEQETSN 480 QKSITEPLPA AEGKRKMEGY QDFAARPVGS RADPEKDSDA DRGAGGATAA EEAGEQGPVP 540 PLPSAPAAPD RGPALGPGAG KQPLTSPSAP ADSKQEPQPC CFAESPDSEP QEPPFPGFPA 600 AQPPLASQSE LEEDKLPAMA DYIANCTVKV DQLGSDDIHN ALKQTPKVLV VQSFDMFKDK 660 DLTGPMNENH GLNYTPLLYS RGNPGIMSPL AKKKLLSQVS GAGLSGSYPY GSPPPLISKK 720 KLIPRDELCS GLPQAHPGQG SDHAAVSRPS VIQHVQSFRS KASEERKGLG DLFKHDKLGR 780 SEPHRCSFSK HHLGPLADSY ALKPDAPEGK DKLLEKRALP HAHVPSFLAD FYSSPHLHSL 840 YRHAEHHLHA EQTSKYACRD AYRESENSSF PAHKHQEKLH VNYLASLHLQ DKKPAPAEAP 900 ADEQPTDLSL PKNLHKPTGK VLGLAHAAPG PQESKGAPQF PAGNGQSRDG HPKACRVSPM 960 TLSAPKKYPE PLSRASRPHH VRLESFRKLE GMVHPVLHRK AGPQAVGAAR PIKRGLEDLD 1020 LVIAGKKARA VSPLDPPKEA CGKDKGAELE GEGGKAAAAH GGPGGAGGGA GAGAGGAAAD 1080 GHKAALSSPI FPGLYSGSLC GSGLGSRLPA GYSHSLQYLK NQTVLSPLMQ PLAFHSLVMQ 1140 RGIFTSPTNS QQLYRHLAAA TPVGSSYGDL LHNSIYPLAA INPQAAFPAS QLSSVHPSTK 1200 L 1201 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ARID5B | 479217 | J9NV13 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ARID5B | 102169735 | A0A452F8Y8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ARID5B | 84159 | Q14865 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Arid5b | 71371 | Q8BM75 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ARID5B | 745725 | K7DSK8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ARID5B | 100352095 | G1U8W9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | arid5b | E7F888 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0003713 | transcription coactivator activity |
| GO:0044212 | transcription regulatory region DNA binding |
| GO:0030325 | adrenal gland development |
| GO:0048468 | cell development |
| GO:1990830 | cellular response to leukemia inhibitory factor |
| GO:0060325 | face morphogenesis |
| GO:0045444 | fat cell differentiation |
| GO:0060613 | fat pad development |
| GO:0008585 | female gonad development |
| GO:0010761 | fibroblast migration |
| GO:0001822 | kidney development |
| GO:0008584 | male gonad development |
| GO:0035264 | multicellular organism growth |
| GO:0048644 | muscle organ morphogenesis |
| GO:0006807 | nitrogen compound metabolic process |
| GO:0048008 | platelet-derived growth factor receptor signaling pathway |
| GO:0051091 | positive regulation of DNA-binding transcription factor activity |
| GO:0009791 | post-embryonic development |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |
| GO:0048705 | skeletal system morphogenesis |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51011 | ARID |
| Pfam ID | Pfam Term |
|---|---|
| PF01388 | ARID |