| Tag | Content |
|---|---|
| Uniprot ID | K7BGT3; A0A2J8MJD7; |
| Entrez ID | 745644 |
| Genbank protein ID | JAA26458.1; JAA00529.1; JAA13324.1; JAA34292.1; |
| Genbank nucleotide ID | XM_016938127.1; XM_016938125.1; XM_009437412.2; |
| Ensembl protein ID | ENSPTRP00000066270 |
| Ensembl nucleotide ID | ENSPTRG00000050285 |
| Gene name | Snail family transcriptional repressor 1 |
| Gene symbol | SNAI1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL NPTASLPMLI 60 WDSVLAPQAQ PIAWASLRPQ ESPRAAELTS LSDEDSGKGS QPPSPPSPAP SSFSSTSASS 120 LEAEAYAAFP GLGQVPKQLA QLSDAKDLQA RKAFNCKYCN KEYLSLGALK MHIRSHTLPC 180 VCGTCGKAFS RPWLLQGHVR THTGEKPFSC PHCSRAFADR SNLRAHLQTH SDVKKYQCQA 240 CARTFSRMSL LHKHQESGCS GCPR 264 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SNAI1 | 504492 | E1BMI0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | SNAI1 | 102172917 | A0A452EKN0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SNAI1 | 100071451 | F6Z6C0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | SNAI1 | 6615 | O95863 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Snai1 | 20613 | Q02085 | CPO | E13.5, E14.5, E15.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SNAI1 | 745644 | K7BGT3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SNAI1 | A0A287B2D0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Snai1 | 116490 | Q6AY35 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0005721 | pericentric heterochromatin |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0070888 | E-box binding |
| GO:0019900 | kinase binding |
| GO:0060536 | cartilage morphogenesis |
| GO:0016477 | cell migration |
| GO:0003198 | epithelial to mesenchymal transition involved in endocardial cushion formation |
| GO:0031069 | hair follicle morphogenesis |
| GO:0070828 | heterochromatin organization |
| GO:0060972 | left/right pattern formation |
| GO:0001707 | mesoderm formation |
| GO:0060806 | negative regulation of cell differentiation involved in embryonic placenta development |
| GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator |
| GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
| GO:0010957 | negative regulation of vitamin D biosynthetic process |
| GO:0061314 | Notch signaling involved in heart development |
| GO:0001649 | osteoblast differentiation |
| GO:0030335 | positive regulation of cell migration |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| GO:0045893 | positive regulation of transcription, DNA-templated |
| GO:2000810 | regulation of bicellular tight junction assembly |
| GO:0060021 | roof of mouth development |
| GO:0060707 | trophoblast giant cell differentiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |